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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (35,743) $ (24,476)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 4,695 1,777
Depreciation 166 150
Amortization of premiums on marketable securities 126 332
Non-cash lease expense 180 314
Other, net (88)  
Change in operating assets and liabilities:    
Prepaid expenses and other assets (308) (570)
Operating lease right-of-use assets and liabilities 1,612  
Accounts payable (1,342) 762
Accrued expenses (975) (434)
Net cash used in operating activities (31,677) (22,145)
Cash flows from investing activities:    
Purchase of property and equipment (4,296) (586)
Purchase of marketable securities (149,223) (185,224)
Maturities of marketable securities 99,415 35,360
Net cash used in investing activities (54,104) (150,450)
Cash flows from financing activities:    
Proceeds from the exercise of stock options and common stock issued under the 2020 ESPP 404 1,418
Net cash provided by financing activities 404 1,418
Net decrease in cash and cash equivalents (85,377) (171,177)
Cash, cash equivalents, and restricted cash    
Cash, cash equivalents, and restricted cash - beginning of period 173,289 361,422
Cash, cash equivalents, and restricted cash - end of period 87,912 190,245
Supplemental disclosures of noncash investing activities    
Accrued purchases of property and equipment $ 1,501  
Supplemental disclosures of cash flow information    
Cash paid for income taxes   $ 4