144 0001758838 XXXXXXXX LIVE 0001699031 GRAIL, Inc. 1525 O'Brien Drive Menlo Park CA 94025 415-528-0644 Andrew Partridge Officer Common Stock ETRADE FINANCIAL CORPORATION 3 EDISON DRIVE ALPHARETTA GA 30005 1705 104226.65 43073334 06/03/2026 NASDAQ Common Stock 06/03/2026 Shares acquired upon vesting of restricted stock units awarded under Issuer's equity incentive plans Issuer N 2914 06/03/2026 Services rendered N Andrew Partridge 1525 O'Brien Drive Menlo Park CA 94025 Common Stock 03/09/2026 1445 69201.05 Andrew Partridge 1525 O'Brien Drive Menlo Park CA 94025 Common Stock 04/08/2026 35240 1759180.8 Represents an estimate of shares expected to be sold to cover tax obligations upon vesting of restricted stock units on June 3rd, 2026, based on an estimated price per share of $61.13, which was the closing price of a share of the Company's common stock on June 3rd, 2026. 06/03/2026 /s/Donald Lang, as Attorney-in-Fact for Andrew Partridge