<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2017-07-25</periodOfReport>

    <issuer>
        <issuerCik>0001275283</issuerCik>
        <issuerName>REYNOLDS AMERICAN INC</issuerName>
        <issuerTradingSymbol>RAI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001303523</rptOwnerCik>
            <rptOwnerName>British American Tobacco p.l.c.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>GLOBE HOUSE</rptOwnerStreet1>
            <rptOwnerStreet2>4 TEMPLE PLACE</rptOwnerStreet2>
            <rptOwnerCity>LONDON</rptOwnerCity>
            <rptOwnerState>X0</rptOwnerState>
            <rptOwnerZipCode>WC2R 2PG</rptOwnerZipCode>
            <rptOwnerStateDescription>UNITED KINGDOM</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001645463</rptOwnerCik>
            <rptOwnerName>Louisville Securities Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>GLOBE HOUSE</rptOwnerStreet1>
            <rptOwnerStreet2>4 TEMPLE PLACE</rptOwnerStreet2>
            <rptOwnerCity>LONDON</rptOwnerCity>
            <rptOwnerState>X0</rptOwnerState>
            <rptOwnerZipCode>WC2R 2PG</rptOwnerZipCode>
            <rptOwnerStateDescription>UNITED KINGDOM</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001699021</rptOwnerCik>
            <rptOwnerName>BATUS Holdings Inc</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>103 FOULK ROAD, SUITE 201-3</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>WILMINGTON</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19803</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2017-07-25</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>824757460</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1426125631</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On July 25, 2017, through a merger between a wholly-owned subsidiary of British American Tobacco p.l.c. (&quot;BAT&quot;) and Reynolds American Inc. (&quot;RAI&quot;), each issued and outstanding share of common stock, par value $0.0001 per share, of RAI (&quot;RAI common stock&quot;) (other than shares owned by BAT and its subsidiaries and shares held by stockholders who have properly asserted (and not lost or effectively withdrawn) a demand for appraisal rights) was automatically converted into the right to receive the merger consideration, consisting of (1) a number of BAT American depositary shares (&quot;BAT ADSs&quot;) representing 0.5260 of an ordinary share, nominal value 25 pence per share, of BAT (&quot;BAT ordinary share&quot;) plus (2) $29.44 in cash, without interest. On July 24, 2017, the last trading day for RAI common stock, the closing price of RAI common stock was $65.40 per share, the closing price of a BAT ordinary share was 54.13 pounds sterling and the closing price of a BAT ADS was $69.25.</footnote>
        <footnote id="F2">BATUS Holdings Inc. (&quot;BATUS&quot;) is the record holder and direct beneficial owner of 824,757,460 shares (the &quot;BATUS owned shares&quot;) of RAI common stock. Brown &amp; Williamson Holdings, Inc. (&quot;B&amp;W&quot;) is the record and direct beneficial owner of 601,368,171 shares (the &quot;B&amp;W owned shares&quot; and, together with the BATUS owned shares, the &quot;Shares&quot;) of RAI common stock.</footnote>
        <footnote id="F3">BATUS may be considered to be an indirect beneficial owner of the B&amp;W owned shares by virtue of its direct ownership of all of the equity and voting power of B&amp;W. Louisville Securities Limited (&quot;Louisville&quot;) may be considered to be an indirect beneficial owner of the Shares by virtue of its direct ownership of all of the equity and voting power of BATUS and indirect ownership of all of the equity and voting power of B&amp;W.  BAT may be considered to be an indirect beneficial owner of the Shares by virtue of its indirect ownership of all the equity and voting power of BATUS and B&amp;W.</footnote>
        <footnote id="F4">BAT and Louisville disclaim beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein and this report shall not be deemed an admission that either BAT or Louisville is a beneficial owner of RAI common stock for purposes of Section 16 or for any other purpose.  BATUS disclaims beneficial ownership of the B&amp;W owned shares except to the extent of its pecuniary interest therein and this report shall not be deemed an admission that BATUS is a beneficial owner of the B&amp;W owned shares for purposes of Section 16 or for any other purpose.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Paul McCrory, Company Secretary, on behalf of British American Tobacco p.l.c.</signatureName>
        <signatureDate>2017-07-25</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Robert J. Casey, Director, on behalf of Louisville Securities Limited</signatureName>
        <signatureDate>2017-07-25</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ L. Brent Cotton, Director, on behalf of BATUS Holdings Inc.</signatureName>
        <signatureDate>2017-07-25</signatureDate>
    </ownerSignature>
</ownershipDocument>
