X0206 3 2021-06-01 0 0001698530 EXICURE, INC. XCUR 0001865732 Papadimas Elias D. C/O EXICURE, INC. 2430 N. HALSTED ST. CHICAGO IL 60614 0 1 0 0 Chief Accounting Officer Common Stock 6537 D Employee Stock Option (right to buy) 1.03 2025-05-21 Common Stock 49649 D Employee Stock Option (right to buy) 4.21 2027-01-03 Common Stock 4964 D Employee Stock Option (right to buy) 3.00 2028-02-14 Common Stock 37004 D Employee Stock Option (right to buy) 2.99 2029-12-09 Common Stock 100000 D Employee Stock Option (right to buy) 1.90 2031-04-26 Common Stock 120000 D Employee Stock Option (right to buy) 1.90 2031-04-26 Common Stock 63800 D Fully vested and exercisable. The shares subject to the option vested or will vest as to 1/48th of the underlying shares monthly from the vesting commencement date of January 2, 2018, provided the Reporting Person remains in continuous service on each vesting date. The shares subject to the option vested or will vest as to 1/48th of the underlying shares monthly from the vesting commencement date of December 10, 2019, provided the Reporting Person remains in continuous service on each vesting date. The shares subject to the option vested or will vest as to 1/48th of the underlying shares monthly from the vesting commencement date of April 27, 2021, provided the Reporting Person remains in continuous service on each vesting date. Exhibit List - Exhibit 24 - Power of Attorney /s/ David Giljohann, Attorney-in-Fact 2021-06-15