Exhibit 13.1

CERTIFICATION

The certification set forth below is being submitted in conntion with the annual report of Banco Santander México, S.A., Institución de Banca Múltiple, Grupo Financiero Santander México on Form 20-F for the year ended December 31, 2022 (the “Report”) for the purpose of complying with Rule 13a-14(b) or Rule 15d-14(b) of the Securities Exchange Act of 1934 (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code. Felipe Francisco García Ascencio, the Executive President and Chief Executive Officer of Banco Santander México, S.A., Institución de Banca Múltiple, Grupo Financiero Santander México, certifies that, to the best of his knowledge:

1.the Report fully complies with the requirements of Section 13(a) or 15(d) of the Exchange Act; and

2.the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of Banco Santander México, S.A., Institución de Banca Múltiple, Grupo Financiero Santander México.

Date: February 28, 2023

	/s/ Felipe Francisco García Ascencio
Name:	Felipe Francisco García Ascencio
Title:	Chief Executive Officer