Exhibit 15.2

Deloitte Accountants B.V.

Audit & Assurance

None

Wilhelminakade 1

3072 AP Rotterdam

P.O. Box 2031

3000 CA Rotterdam

The Netherlands

                                Tel: +31 (0)88 288 2888

                            www.deloitte.nl

March 20, 2025

Securities and Exchange Commission

100 F Street, N.E.

WASHINGTON, D.C. 20549-7561

Dear Sirs/Madams,

We have read Item 16F of argenx SE's Form 20-F dated March 20, 2025, and we agree with the statements made in paragraphs 3 and 5 therein. We have no basis on which to agree or disagree with the statements made in paragraphs 1, 2 and 4.

Yours truly,

/s/ Deloitte Accountants B.V.