The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
Adobe Inc | Common Stock | 00724F101 | 53,822 | 107,619 | SH | SOLE | 107,619 | 0 | 0 | ||
Aerojet Rocketdyne Holdings In | Common Stock | 007800105 | 1,271 | 24,044 | SH | SOLE | 24,044 | 0 | 0 | ||
AeroVironment Inc | Common Stock | 008073108 | 35,344 | 406,726 | SH | SOLE | 406,726 | 0 | 0 | ||
Alibaba Group Holding Ltd | ADR | 01609W102 | 125,075 | 537,424 | SH | SOLE | 537,424 | 0 | 0 | ||
Align Technology Inc | Common Stock | 016255101 | 2,173 | 4,066 | SH | SOLE | 4,066 | 0 | 0 | ||
Allegheny Technologies Inc | Common Stock | 01741R102 | 259 | 15,429 | SH | SOLE | 15,429 | 0 | 0 | ||
Alphabet Inc | Common Stock | 02079K107 | 64,664 | 36,911 | SH | SOLE | 36,911 | 0 | 0 | ||
Altair Engineering Inc | Common Stock | 021369103 | 5,978 | 102,744 | SH | SOLE | 102,744 | 0 | 0 | ||
Amazon.com Inc | Common Stock | 023135106 | 73,294 | 22,504 | SH | SOLE | 22,504 | 0 | 0 | ||
AMETEK Inc | Common Stock | 031100100 | 1,526 | 12,621 | SH | SOLE | 12,621 | 0 | 0 | ||
ANSYS Inc | Common Stock | 03662Q105 | 28,109 | 77,265 | SH | SOLE | 77,265 | 0 | 0 | ||
Apple Inc | Common Stock | 037833100 | 121,398 | 914,900 | SH | SOLE | 914,900 | 0 | 0 | ||
AquaBounty Technologies Inc | Common Stock | 03842K200 | 75,690 | 8,640,421 | SH | SOLE | 8,640,421 | 0 | 0 | ||
Arcturus Therapeutics Holdings | Common Stock | 03969T109 | 171,742 | 3,959,019 | SH | SOLE | 3,959,019 | 0 | 0 | ||
Autodesk Inc | Common Stock | 052769106 | 22,565 | 73,902 | SH | SOLE | 73,902 | 0 | 0 | ||
Baidu Inc | ADR | 056752108 | 488,870 | 2,260,776 | SH | SOLE | 2,153,071 | 59,335 | 48,370 | ||
Renishaw PLC | Common Stock | G75006117 | 5,789 | 73,622 | SH | SOLE | 73,622 | 0 | 0 | ||
CareDx Inc | Common Stock | 14167L103 | 294,315 | 4,062,322 | SH | SOLE | 4,062,322 | 0 | 0 | ||
Carpenter Technology Corp | Common Stock | 144285103 | 227 | 7,804 | SH | SOLE | 7,804 | 0 | 0 | ||
Castle Biosciences Inc | Common Stock | 14843C105 | 138,906 | 2,068,592 | SH | SOLE | 2,068,592 | 0 | 0 | ||
Cellectis SA | ADR | 15117K103 | 180,736 | 6,679,077 | SH | SOLE | 6,137,609 | 528,536 | 12,932 | ||
Cerus Corp | Common Stock | 157085101 | 204,640 | 29,572,265 | SH | SOLE | 27,283,159 | 616,222 | 1,672,884 | ||
Codexis Inc | Common Stock | 192005106 | 86,493 | 3,962,106 | SH | SOLE | 3,962,106 | 0 | 0 | ||
Deere & Co | Common Stock | 244199105 | 66,791 | 248,248 | SH | SOLE | 248,248 | 0 | 0 | ||
DuPont de Nemours Inc | Common Stock | 26614N102 | 173 | 2,427 | SH | SOLE | 2,427 | 0 | 0 | ||
Eastman Chemical Co | Common Stock | 277432100 | 168 | 1,673 | SH | SOLE | 1,673 | 0 | 0 | ||
Editas Medicine Inc | Common Stock | 28106W103 | 709,903 | 10,125,564 | SH | SOLE | 8,674,905 | 1,008,363 | 442,296 | ||
ExOne Co/The | Common Stock | 302104104 | 22,542 | 2,375,334 | SH | SOLE | 1,994,515 | 0 | 380,819 | ||
FLIR Systems Inc | Common Stock | 302445101 | 64,536 | 1,472,422 | SH | SOLE | 1,472,422 | 0 | 0 | ||
Facebook Inc | Common Stock | 30303M102 | 178,733 | 654,316 | SH | SOLE | 627,531 | 26,785 | 0 | ||
FARO Technologies Inc | Common Stock | 311642102 | 1,518 | 21,492 | SH | SOLE | 21,492 | 0 | 0 | ||
Fate Therapeutics Inc | Common Stock | 31189P102 | 263,852 | 2,901,700 | SH | SOLE | 2,901,700 | 0 | 0 | ||
General Electric Co | Common Stock | 369604103 | 1,468 | 135,928 | SH | SOLE | 135,928 | 0 | 0 | ||
Grayscale Bitcoin Trust BTC | Open-End Fund | 389637109 | 233,831 | 7,307,228 | SH | SOLE | 6,171,965 | 898,680 | 236,583 | ||
Guardant Health Inc | Common Stock | 40131M109 | 69,664 | 540,537 | SH | SOLE | 540,537 | 0 | 0 | ||
Guidewire Software Inc | Common Stock | 40171V100 | 28,047 | 217,878 | SH | SOLE | 217,878 | 0 | 0 | ||
HDFC Bank Ltd | ADR | 40415F101 | 20,060 | 277,611 | SH | SOLE | 277,611 | 0 | 0 | ||
HP Inc | Common Stock | 40434L105 | 6,929 | 281,788 | SH | SOLE | 281,788 | 0 | 0 | ||
Hexcel Corp | Common Stock | 428291108 | 193 | 3,986 | SH | SOLE | 3,986 | 0 | 0 | ||
HubSpot Inc | Common Stock | 443573100 | 56,790 | 143,250 | SH | SOLE | 143,250 | 0 | 0 | ||
Illumina Inc | Common Stock | 452327109 | 18,716 | 50,585 | SH | SOLE | 0 | 50,585 | 0 | ||
Incyte Corp | Common Stock | 45337C102 | 155,031 | 1,782,380 | SH | SOLE | 1,782,380 | 0 | 0 | ||
Intellia Therapeutics Inc | Common Stock | 45826J105 | 608,827 | 11,191,670 | SH | SOLE | 8,979,307 | 1,384,498 | 827,865 | ||
Interactive Brokers Group Inc | Common Stock | 45841N107 | 251 | 4,113 | SH | SOLE | 4,113 | 0 | 0 | ||
Intercontinental Exchange Inc | Common Stock | 45866F104 | 525,489 | 4,557,974 | SH | SOLE | 4,193,764 | 253,798 | 110,412 | ||
Intuit Inc | Common Stock | 461202103 | 33,933 | 89,333 | SH | SOLE | 89,333 | 0 | 0 | ||
Intuitive Surgical Inc | Common Stock | 46120E602 | 21,164 | 25,870 | SH | SOLE | 25,870 | 0 | 0 | ||
OC Oerlikon Corp AG | Common Stock | H59187106 | 1,265 | 122,093 | SH | SOLE | 122,093 | 0 | 0 | ||
Invitae Corp | Common Stock | 46185L103 | 1,128,918 | 27,001,138 | SH | SOLE | 23,858,013 | 2,155,092 | 988,033 | ||
Ionis Pharmaceuticals Inc | Common Stock | 462222100 | 135,671 | 2,399,554 | SH | SOLE | 2,399,554 | 0 | 0 | ||
Iovance Biotherapeutics Inc | Common Stock | 462260100 | 709,819 | 15,297,822 | SH | SOLE | 14,517,914 | 466,145 | 313,763 | ||
Iridium Communications Inc | Common Stock | 46269C102 | 274,104 | 6,970,230 | SH | SOLE | 6,142,620 | 560,242 | 267,368 | ||
JD.com Inc | ADR | 47215P106 | 143,961 | 1,637,783 | SH | SOLE | 1,637,783 | 0 | 0 | ||
SGL Carbon SE | Common Stock | D6949M108 | 185 | 41,875 | SH | SOLE | 41,875 | 0 | 0 | ||
Kaiser Aluminum Corp | Common Stock | 483007704 | 1,481 | 14,970 | SH | SOLE | 14,970 | 0 | 0 | ||
Komatsu Ltd | ADR | 500458401 | 41,289 | 1,491,525 | SH | SOLE | 1,491,525 | 0 | 0 | ||
Kratos Defense & Security Solu | Common Stock | 50077B207 | 61,266 | 2,233,535 | SH | SOLE | 2,233,535 | 0 | 0 | ||
Henkel AG & Co KGaA | Preference | D3207M110 | 153 | 1,346 | SH | SOLE | 1,346 | 0 | 0 | ||
Bertrandt AG | Common Stock | D1014N107 | 1,224 | 25,157 | SH | SOLE | 25,157 | 0 | 0 | ||
LendingClub Corp | Common Stock | 52603A208 | 78,727 | 7,455,162 | SH | SOLE | 6,574,964 | 183,369 | 696,829 | ||
LendingTree Inc | Common Stock | 52603B107 | 550,388 | 2,010,255 | SH | SOLE | 1,767,482 | 160,894 | 81,879 | ||
Dassault Systemes SE | Common Stock | F2457H472 | 5,185 | 25,529 | SH | SOLE | 25,529 | 0 | 0 | ||
Lincoln Electric Holdings Inc | Common Stock | 533900106 | 1,105 | 9,506 | SH | SOLE | 9,506 | 0 | 0 | ||
Siemens AG | Common Stock | D69671218 | 1,063 | 7,358 | SH | SOLE | 7,358 | 0 | 0 | ||
Materialise NV | ADR | 57667T100 | 464,259 | 8,564,081 | SH | SOLE | 8,257,636 | 75,126 | 231,319 | ||
MercadoLibre Inc | Common Stock | 58733R102 | 183,669 | 109,639 | SH | SOLE | 100,254 | 9,385 | 0 | ||
Microsoft Corp | Common Stock | 594918104 | 4,780 | 21,490 | SH | SOLE | 21,490 | 0 | 0 | ||
Bezeq The Israeli Telecommunic | Common Stock | M2012Q100 | 1,372 | 1,378,112 | SH | SOLE | 1,378,112 | 0 | 0 | ||
Moog Inc | Common Stock | 615394202 | 1,157 | 14,586 | SH | SOLE | 14,586 | 0 | 0 | ||
Danel Adir Yeoshua Ltd | Common Stock | M27013107 | 2,240 | 13,601 | SH | SOLE | 13,601 | 0 | 0 | ||
Hilan Ltd | Common Stock | M5299H123 | 1,816 | 38,306 | SH | SOLE | 38,306 | 0 | 0 | ||
Nano Dimension Ltd | ADR | 63008G203 | 76,379 | 8,393,249 | SH | SOLE | 8,393,249 | 0 | 0 | ||
NanoString Technologies Inc | Common Stock | 63009R109 | 261,987 | 3,917,273 | SH | SOLE | 3,465,066 | 447,044 | 5,163 | ||
Elbit Systems Ltd | Common Stock | M3760D101 | 18,619 | 142,345 | SH | SOLE | 142,345 | 0 | 0 | ||
SBI Holdings Inc/Japan | Common Stock | J6991H100 | 545 | 23,000 | SH | SOLE | 23,000 | 0 | 0 | ||
Partner Communications Co Ltd | Common Stock | M78465107 | 2,327 | 422,156 | SH | SOLE | 422,156 | 0 | 0 | ||
Netflix Inc | Common Stock | 64110L106 | 111,616 | 206,418 | SH | SOLE | 204,524 | 1,894 | 0 | ||
Nice Ltd | ADR | 653656108 | 2,009 | 7,084 | SH | SOLE | 7,084 | 0 | 0 | ||
FirstRand Ltd | Common Stock | S5202Z131 | 30 | 13,580 | SH | SOLE | 13,580 | 0 | 0 | ||
NVIDIA Corp | Common Stock | 67066G104 | 95,357 | 182,606 | SH | SOLE | 175,657 | 6,949 | 0 | ||
NuVasive Inc | Common Stock | 670704105 | 1,007 | 17,875 | SH | SOLE | 17,875 | 0 | 0 | ||
Matrix IT Ltd | Common Stock | M6859E153 | 1,570 | 69,419 | SH | SOLE | 69,419 | 0 | 0 | ||
Toray Industries Inc | Common Stock | J89494116 | 170 | 28,708 | SH | SOLE | 28,708 | 0 | 0 | ||
PTC Inc | Common Stock | 69370C100 | 6,435 | 53,804 | SH | SOLE | 53,804 | 0 | 0 | ||
Pacific Biosciences of Califor | Common Stock | 69404D108 | 739,410 | 28,504,629 | SH | SOLE | 27,646,542 | 413,947 | 444,140 | ||
One Software Technologies Ltd | Common Stock | M75260113 | 2,741 | 20,737 | SH | SOLE | 20,737 | 0 | 0 | ||
PayPal Holdings Inc | Common Stock | 70450Y103 | 605,334 | 2,584,689 | SH | SOLE | 2,340,483 | 190,694 | 53,512 | ||
Personalis Inc | Common Stock | 71535D106 | 248,165 | 6,778,623 | SH | SOLE | 6,778,623 | 0 | 0 | ||
Straumann Holding AG | Common Stock | H8300N119 | 5,972 | 5,112 | SH | SOLE | 5,112 | 0 | 0 | ||
Pinduoduo Inc | ADR | 722304102 | 32,405 | 182,390 | SH | SOLE | 182,390 | 0 | 0 | ||
Pinterest Inc | Common Stock | 72352L106 | 403,953 | 6,129,780 | SH | SOLE | 5,156,525 | 865,943 | 107,312 | ||
Pluristem Therapeutics Inc | Common Stock | 72940R300 | 27,993 | 3,959,344 | SH | SOLE | 3,959,344 | 0 | 0 | ||
Proto Labs Inc | Common Stock | 743713109 | 631,996 | 4,119,922 | SH | SOLE | 3,584,210 | 346,687 | 189,025 | ||
Redhill Biopharma Ltd | ADR | 757468103 | 1,347 | 166,749 | SH | SOLE | 166,749 | 0 | 0 | ||
Roku Inc | Common Stock | 77543R102 | 1,785,212 | 5,376,822 | SH | SOLE | 4,706,975 | 479,916 | 189,931 | ||
salesforce.com Inc | Common Stock | 79466L302 | 49,691 | 223,302 | SH | SOLE | 223,302 | 0 | 0 | ||
Charles Schwab Corp/The | Common Stock | 808513105 | 25,788 | 486,201 | SH | SOLE | 486,201 | 0 | 0 | ||
Seres Therapeutics Inc | Common Stock | 81750R102 | 336,661 | 13,741,254 | SH | SOLE | 12,097,738 | 1,158,078 | 485,438 | ||
Shopify Inc | Common Stock | 82509L107 | 544,582 | 481,101 | SH | SOLE | 435,748 | 34,177 | 11,176 | ||
Snap Inc | Common Stock | 83304A106 | 166,408 | 3,323,503 | SH | SOLE | 3,323,503 | 0 | 0 | ||
Splunk Inc | Common Stock | 848637104 | 343,054 | 2,019,273 | SH | SOLE | 1,781,886 | 181,067 | 56,320 | ||
Square Inc | Common Stock | 852234103 | 1,541,416 | 7,082,410 | SH | SOLE | 6,294,595 | 582,232 | 205,583 | ||
Stryker Corp | Common Stock | 863667101 | 1,041 | 4,247 | SH | SOLE | 4,247 | 0 | 0 | ||
Syros Pharmaceuticals Inc | Common Stock | 87184Q107 | 98,098 | 9,041,321 | SH | SOLE | 8,237,117 | 186,593 | 617,611 | ||
Taiwan Semiconductor Manufactu | ADR | 874039100 | 491,486 | 4,507,394 | SH | SOLE | 3,956,306 | 398,575 | 152,513 | ||
Teladoc Health Inc | Common Stock | 87918A105 | 1,566,153 | 7,832,332 | SH | SOLE | 7,209,660 | 449,485 | 173,187 | ||
Tencent Holdings Ltd | ADR | 88032Q109 | 454,574 | 6,323,184 | SH | SOLE | 5,930,690 | 301,409 | 91,085 | ||
Teradyne Inc | Common Stock | 880770102 | 28,539 | 238,047 | SH | SOLE | 238,047 | 0 | 0 | ||
Tesla Inc | Common Stock | 88160R101 | 2,917,399 | 4,134,226 | SH | SOLE | 3,778,990 | 350,036 | 5,200 | ||
Teva Pharmaceutical Industries | ADR | 881624209 | 1,735 | 179,802 | SH | SOLE | 179,802 | 0 | 0 | ||
Trade Desk Inc/The | Common Stock | 88339J105 | 65,348 | 81,583 | SH | SOLE | 81,583 | 0 | 0 | ||
3D Systems Corp | Common Stock | 88554D205 | 8,581 | 818,772 | SH | SOLE | 818,772 | 0 | 0 | ||
3M Co | Common Stock | 88579Y101 | 148 | 845 | SH | SOLE | 845 | 0 | 0 | ||
Trimble Inc | Common Stock | 896239100 | 74,778 | 1,119,940 | SH | SOLE | 1,119,940 | 0 | 0 | ||
Twilio Inc | Common Stock | 90138F102 | 607,187 | 1,793,759 | SH | SOLE | 1,588,760 | 156,491 | 48,508 | ||
Twist Bioscience Corp | Common Stock | 90184D100 | 830,357 | 5,876,971 | SH | SOLE | 5,570,693 | 139,968 | 166,310 | ||
2U Inc | Common Stock | 90214J101 | 530,596 | 13,261,577 | SH | SOLE | 11,265,301 | 1,396,560 | 599,716 | ||
Ultra Clean Holdings Inc | Common Stock | 90385V107 | 1,222 | 39,220 | SH | SOLE | 39,220 | 0 | 0 | ||
United Parcel Service Inc | Common Stock | 911312106 | 932 | 5,536 | SH | SOLE | 5,536 | 0 | 0 | ||
Veracyte Inc | Common Stock | 92337F107 | 441,822 | 9,027,827 | SH | SOLE | 8,814,751 | 213,076 | 0 | ||
Verisk Analytics Inc | Common Stock | 92345Y106 | 16,133 | 77,714 | SH | SOLE | 77,714 | 0 | 0 | ||
Workday Inc | Common Stock | 98138H101 | 39,845 | 166,290 | SH | SOLE | 166,290 | 0 | 0 | ||
Xilinx Inc | Common Stock | 983919101 | 29,107 | 205,309 | SH | SOLE | 164,097 | 41,212 | 0 | ||
Xerox Holdings Corp | Common Stock | 98421M106 | 167 | 7,200 | SH | SOLE | 7,200 | 0 | 0 | ||
Zillow Group Inc | Common Stock | 98954M200 | 841,260 | 6,481,205 | SH | SOLE | 5,714,512 | 571,735 | 194,958 | ||
Koninklijke DSM NV | Common Stock | N5017D122 | 145 | 843 | SH | SOLE | 843 | 0 | 0 | ||
Arkema SA | Common Stock | F0392W125 | 148 | 1,294 | SH | SOLE | 1,294 | 0 | 0 | ||
MGI Digital Graphic Technology | Common Stock | F4090S113 | 5,827 | 99,824 | SH | SOLE | 99,824 | 0 | 0 | ||
Sandvik AB | Common Stock | W74857165 | 182 | 7,402 | SH | SOLE | 7,402 | 0 | 0 | ||
Hexagon AB | Common Stock | W40063104 | 1,655 | 18,090 | SH | SOLE | 18,090 | 0 | 0 | ||
Cellcom Israel Ltd | Common Stock | M2196U109 | 2,106 | 427,345 | SH | SOLE | 427,345 | 0 | 0 | ||
Evonik Industries AG | Common Stock | D2R90Y117 | 175 | 5,337 | SH | SOLE | 5,337 | 0 | 0 | ||
Fattal Holdings 1998 Ltd | Common Stock | M4148G105 | 2,704 | 25,141 | SH | SOLE | 25,141 | 0 | 0 | ||
Meituan | Common Stock | G59669104 | 54,136 | 1,424,815 | SH | SOLE | 1,424,815 | 0 | 0 | ||
SLM Solutions Group AG | Common Stock | D6T690109 | 9,083 | 424,298 | SH | SOLE | 424,298 | 0 | 0 | ||
ZhongAn Online P&C Insurance C | Common Stock | Y989DF109 | 36,084 | 7,728,745 | SH | SOLE | 7,728,745 | 0 | 0 | ||
Adyen NV | Common Stock | N3501V104 | 73,671 | 31,634 | SH | SOLE | 31,634 | 0 | 0 | ||
Atlassian Corp PLC | Common Stock | G06242104 | 51,296 | 219,336 | SH | SOLE | 219,336 | 0 | 0 | ||
Medtronic PLC | Common Stock | G5960L103 | 1,033 | 8,819 | SH | SOLE | 8,819 | 0 | 0 | ||
Sapiens International Corp NV | Common Stock | G7T16G103 | 1,677 | 54,784 | SH | SOLE | 54,784 | 0 | 0 | ||
CRISPR Therapeutics AG | Common Stock | H17182108 | 1,594,331 | 10,412,976 | SH | SOLE | 9,317,964 | 741,603 | 353,409 | ||
Spotify Technology SA | Common Stock | L8681T102 | 741,445 | 2,356,336 | SH | SOLE | 2,082,876 | 197,855 | 75,605 | ||
Allot Ltd | Common Stock | M0854Q105 | 1,732 | 164,625 | SH | SOLE | 164,625 | 0 | 0 | ||
AudioCodes Ltd | Common Stock | M15342104 | 1,380 | 50,074 | SH | SOLE | 50,074 | 0 | 0 | ||
Camtek Ltd/Israel | Common Stock | M20791105 | 2,003 | 91,434 | SH | SOLE | 91,434 | 0 | 0 | ||
Ceragon Networks Ltd | Common Stock | M22013102 | 1,816 | 653,123 | SH | SOLE | 653,123 | 0 | 0 | ||
Check Point Software Technolog | Common Stock | M22465104 | 1,740 | 13,093 | SH | SOLE | 13,093 | 0 | 0 | ||
Compugen Ltd | Common Stock | M25722105 | 206,879 | 17,083,306 | SH | SOLE | 16,714,552 | 219,844 | 148,910 | ||
CyberArk Software Ltd | Common Stock | M2682V108 | 2,411 | 14,918 | SH | SOLE | 14,918 | 0 | 0 | ||
Evogene Ltd | Common Stock | M4119S104 | 21,594 | 4,594,499 | SH | SOLE | 4,594,499 | 0 | 0 | ||
Fiverr International Ltd | Common Stock | M4R82T106 | 2,030 | 10,406 | SH | SOLE | 10,406 | 0 | 0 | ||
Ituran Location and Control Lt | Common Stock | M6158M104 | 2,271 | 119,194 | SH | SOLE | 119,194 | 0 | 0 | ||
Nova Measuring Instruments Ltd | Common Stock | M7516K103 | 2,041 | 28,913 | SH | SOLE | 28,913 | 0 | 0 | ||
Radware Ltd | Common Stock | M81873107 | 1,893 | 68,213 | SH | SOLE | 68,213 | 0 | 0 | ||
Stratasys Ltd | Common Stock | M85548101 | 250,456 | 12,087,661 | SH | SOLE | 9,346,918 | 1,389,700 | 1,351,043 | ||
Taro Pharmaceutical Industries | Common Stock | M8737E108 | 2,057 | 28,021 | SH | SOLE | 28,021 | 0 | 0 | ||
Tower Semiconductor Ltd | Common Stock | M87915274 | 2,186 | 84,677 | SH | SOLE | 84,677 | 0 | 0 | ||
UroGen Pharma Ltd | Common Stock | M96088105 | 1,329 | 73,769 | SH | SOLE | 73,769 | 0 | 0 | ||
Wix.com Ltd | Common Stock | M98068105 | 1,462 | 5,848 | SH | SOLE | 5,848 | 0 | 0 | ||
NXP Semiconductors NV | Common Stock | N6596X109 | 51,938 | 326,634 | SH | SOLE | 326,634 | 0 | 0 | ||
DocuSign Inc | Common Stock | 256163106 | 484,619 | 2,180,021 | SH | SOLE | 2,054,410 | 85,716 | 39,895 | ||
Zscaler Inc | Common Stock | 98980G102 | 9,862 | 49,382 | SH | SOLE | 621 | 48,761 | 0 | ||
GMO internet Inc | Common Stock | J1822R104 | 24 | 800 | SH | SOLE | 800 | 0 | 0 | ||
Discovery Ltd | Common Stock | S2192Y109 | 23,920 | 2,285,684 | SH | SOLE | 2,285,684 | 0 | 0 | ||
Inmode Ltd | Common Stock | M5425M103 | 1,961 | 41,303 | SH | SOLE | 41,303 | 0 | 0 | ||
Perion Network Ltd | Common Stock | M78673114 | 2,774 | 217,906 | SH | SOLE | 217,906 | 0 | 0 | ||
Silvergate Capital Corp | Common Stock | 82837P408 | 46,874 | 630,789 | SH | SOLE | 630,789 | 0 | 0 | ||
Meituan | ADR | 58533E103 | 231 | 3,080 | SH | SOLE | 3,080 | 0 | 0 | ||
Z Holdings Corp | Common Stock | J9894K105 | 37,930 | 6,272,007 | SH | SOLE | 6,272,007 | 0 | 0 | ||
Sea Ltd | ADR | 81141R100 | 383,663 | 1,927,472 | SH | SOLE | 1,781,856 | 105,067 | 40,549 | ||
Z Holdings Corp | ADR | 98877X101 | 606 | 50,017 | SH | SOLE | 50,017 | 0 | 0 | ||
Pure Storage Inc | Common Stock | 74624M102 | 930,656 | 41,161,248 | SH | SOLE | 37,511,255 | 2,624,570 | 1,025,423 | ||
Synopsys Inc | Common Stock | 871607107 | 264,731 | 1,021,182 | SH | SOLE | 962,854 | 32,822 | 25,506 | ||
HUYA Inc | ADR | 44852D108 | 231,208 | 11,600,993 | SH | SOLE | 10,642,894 | 620,710 | 337,389 | ||
RADA Electronic Industries Ltd | Common Stock | M81863124 | 2,441 | 250,312 | SH | SOLE | 250,312 | 0 | 0 | ||
PagerDuty Inc | Common Stock | 69553P100 | 481,545 | 11,547,833 | SH | SOLE | 9,992,000 | 1,044,146 | 511,687 | ||
Caterpillar Inc | Common Stock | 149123101 | 45,433 | 249,604 | SH | SOLE | 249,604 | 0 | 0 | ||
Rockwell Automation Inc | Common Stock | 773903109 | 14,011 | 55,862 | SH | SOLE | 55,862 | 0 | 0 | ||
Arconic Corp | Common Stock | 03966V107 | 1,240 | 41,618 | SH | SOLE | 41,618 | 0 | 0 | ||
Lightspeed POS Inc | Common Stock | 53227R106 | 46,466 | 660,370 | SH | SOLE | 660,370 | 0 | 0 | ||
Adaptive Biotechnologies Corp | Common Stock | 00650F109 | 91,397 | 1,545,703 | SH | SOLE | 1,545,703 | 0 | 0 | ||
10X Genomics Inc | Common Stock | 88025U109 | 75,543 | 533,496 | SH | SOLE | 533,496 | 0 | 0 | ||
Crowdstrike Holdings Inc | Common Stock | 22788C105 | 54,438 | 257,002 | SH | SOLE | 257,002 | 0 | 0 | ||
Okta Inc | Common Stock | 679295105 | 46,491 | 182,849 | SH | SOLE | 182,849 | 0 | 0 | ||
Bitcoin Fund/The | Closed-End Fund | 09175G104 | 11,810 | 313,436 | SH | SOLE | 0 | 0 | 313,436 | ||
Schrodinger Inc/United States | Common Stock | 80810D103 | 110,492 | 1,395,453 | SH | SOLE | 1,395,453 | 0 | 0 | ||
Slack Technologies Inc | Common Stock | 83088V102 | 46,738 | 1,106,491 | SH | SOLE | 17,027 | 1,089,464 | 0 | ||
TCS Group Holding PLC | GDR | 87238U203 | 21,861 | 664,465 | SH | SOLE | 664,465 | 0 | 0 | ||
Phreesia Inc | Common Stock | 71944F106 | 71,433 | 1,316,496 | SH | SOLE | 1,316,496 | 0 | 0 | ||
Virgin Galactic Holdings Inc | Common Stock | 92766K106 | 31,936 | 1,345,793 | SH | SOLE | 1,345,793 | 0 | 0 | ||
Workhorse Group Inc | Common Stock | 98138J206 | 36,558 | 1,848,216 | SH | SOLE | 1,848,216 | 0 | 0 | ||
Adyen NV | ADR | 00783V104 | 53,103 | 1,144,465 | SH | SOLE | 1,144,465 | 0 | 0 | ||
Cie Generale des Etablissement | Common Stock | F61824144 | 1,135 | 8,850 | SH | SOLE | 8,850 | 0 | 0 | ||
voestalpine AG | Common Stock | A9101Y103 | 185 | 5,126 | SH | SOLE | 5,126 | 0 | 0 | ||
Yeahka Ltd | Common Stock | G9835C108 | 20,417 | 4,210,400 | SH | SOLE | 4,210,400 | 0 | 0 | ||
Accolade Inc | Common Stock | 00437E102 | 103,021 | 2,368,304 | SH | SOLE | 2,368,304 | 0 | 0 | ||
Berkeley Lights Inc | Common Stock | 084310101 | 130,942 | 1,464,517 | SH | SOLE | 1,464,517 | 0 | 0 | ||
Vertex Pharmaceuticals Inc | Common Stock | 92532F100 | 192,899 | 816,194 | SH | SOLE | 816,194 | 0 | 0 | ||
BYD Co Ltd | ADR | 05606L100 | 45,616 | 864,427 | SH | SOLE | 864,427 | 0 | 0 | ||
Ayala Pharmaceuticals Inc | Common Stock | 05465V108 | 1,248 | 113,450 | SH | SOLE | 113,450 | 0 | 0 | ||
Biondvax Pharmaceuticals Ltd | ADR | 09073Q105 | 117 | 41,566 | SH | SOLE | 41,566 | 0 | 0 | ||
Kamada Ltd | Common Stock | M6240T109 | 1,349 | 209,833 | SH | SOLE | 209,833 | 0 | 0 | ||
BATM Advanced Communications L | Common Stock | M19199112 | 1,406 | 1,112,971 | SH | SOLE | 1,112,971 | 0 | 0 | ||
Gamida Cell Ltd | Common Stock | M47364100 | 2,702 | 322,026 | SH | SOLE | 322,026 | 0 | 0 | ||
Gilat Satellite Networks Ltd | Common Stock | M51474118 | 2,168 | 332,564 | SH | SOLE | 332,564 | 0 | 0 | ||
PolyPid Ltd | Common Stock | M8001Q118 | 1,423 | 143,728 | SH | SOLE | 143,728 | 0 | 0 | ||
Silicom Ltd | Common Stock | M84116108 | 1,964 | 46,930 | SH | SOLE | 46,930 | 0 | 0 | ||
Nintendo Co Ltd | ADR | 654445303 | 355,828 | 4,419,131 | SH | SOLE | 3,927,962 | 363,970 | 127,199 | ||
Organovo Holdings Inc | Common Stock | 68620A203 | 17,277 | 1,404,620 | SH | SOLE | 1,401,092 | 3,528 | 0 | ||
Surface Oncology Inc | Common Stock | 86877M209 | 23,492 | 2,542,391 | SH | SOLE | 2,542,391 | 0 | 0 | ||
Takeda Pharmaceutical Co Ltd | ADR | 874060205 | 156,851 | 8,618,165 | SH | SOLE | 8,618,165 | 0 | 0 | ||
Niu Technologies | ADR | 65481N100 | 24,899 | 887,653 | SH | SOLE | 887,653 | 0 | 0 | ||
Thermo Fisher Scientific Inc | Common Stock | 883556102 | 88,623 | 190,269 | SH | SOLE | 190,269 | 0 | 0 | ||
Exact Sciences Corp | Common Stock | 30063P105 | 703,849 | 5,312,466 | SH | SOLE | 4,786,293 | 406,610 | 119,563 | ||
ARK Innovation ETF | ETP | 00214Q104 | 363 | 2,914 | SH | SOLE | 2,914 | 0 | 0 | ||
Siemens Energy AG | Common Stock | D6T47E106 | 3 | 74 | SH | SOLE | 74 | 0 | 0 | ||
Snowflake Inc | Common Stock | 833445109 | 28 | 98 | SH | SOLE | 98 | 0 | 0 | ||
Unity Software Inc | Common Stock | 91332U101 | 365,465 | 2,381,348 | SH | SOLE | 2,224,748 | 84,900 | 71,700 | ||
Beam Therapeutics Inc | Common Stock | 07373V105 | 92,386 | 1,131,623 | SH | SOLE | 1,131,623 | 0 | 0 | ||
Novartis AG | Common Stock | H5820Q150 | 201,778 | 2,129,945 | SH | SOLE | 2,129,945 | 0 | 0 | ||
Regeneron Pharmaceuticals Inc | Common Stock | 75886F107 | 218,278 | 451,818 | SH | SOLE | 451,818 | 0 | 0 | ||
Repare Therapeutics Inc | Common Stock | 760273102 | 21,794 | 635,393 | SH | SOLE | 635,393 | 0 | 0 | ||
MarketAxess Holdings Inc | Common Stock | 57060D108 | 9,612 | 16,846 | SH | SOLE | 16,846 | 0 | 0 | ||
Agora Inc | ADR | 00851L103 | 62,105 | 1,569,888 | SH | SOLE | 1,569,888 | 0 | 0 | ||
KE Holdings Inc | ADR | 482497104 | 408,508 | 6,638,093 | SH | SOLE | 5,983,017 | 475,448 | 179,628 | ||
Fastly Inc | Common Stock | 31188V100 | 99,484 | 1,138,656 | SH | SOLE | 1,138,656 | 0 | 0 | ||
Cloudflare Inc | Common Stock | 18915M107 | 55,088 | 724,940 | SH | SOLE | 724,940 | 0 | 0 | ||
Palantir Technologies Inc | Common Stock | 69608A108 | 31,018 | 1,317,122 | SH | SOLE | 1,317,122 | 0 | 0 | ||
Raven Industries Inc | Common Stock | 754212108 | 16,338 | 493,743 | SH | SOLE | 493,743 | 0 | 0 | ||
Zoom Video Communications Inc | Common Stock | 98980L101 | 322,165 | 955,071 | SH | SOLE | 887,568 | 37,973 | 29,530 | ||
Longview Acquisition Corp | Common Stock | 543195101 | 29,834 | 1,507,542 | SH | SOLE | 1,507,542 | 0 | 0 | ||
Honeywell International Inc | Common Stock | 438516106 | 7,971 | 37,476 | SH | SOLE | 37,476 | 0 | 0 | ||
Alphabet Inc | Common Stock | 02079K305 | 164,941 | 94,110 | SH | SOLE | 94,110 | 0 | 0 | ||
Roche Holding AG | ADR | 771195104 | 234,851 | 5,357,003 | SH | SOLE | 5,357,003 | 0 | 0 | ||
ARK Genomic Revolution ETF | ETP | 00214Q302 | 156 | 1,670 | SH | SOLE | 1,670 | 0 | 0 | ||
Sarepta Therapeutics Inc | Common Stock | 803607100 | 41,414 | 242,911 | SH | SOLE | 242,911 | 0 | 0 | ||
Opendoor Technologies Inc | Common Stock | 683712103 | 90,948 | 4,001,226 | SH | SOLE | 4,001,226 | 0 | 0 | ||
BASE Inc | Common Stock | J0433G101 | 20,721 | 219,200 | SH | SOLE | 219,200 | 0 | 0 | ||
Kaspi.KZ JSC | GDR | 48581R205 | 2,587 | 38,548 | SH | SOLE | 38,548 | 0 | 0 | ||
JD Health International Inc | Common Stock | G5074A100 | 134 | 6,925 | SH | SOLE | 6,925 | 0 | 0 | ||
salesforce.com Inc | Common Stock | 79466L302 | 49,691 | 223,302 | SH | SOLE | 223,302 | 0 | 0 | ||
908 Devices Inc | Common Stock | 65443P102 | 24,901 | 437,248 | SH | SOLE | 437,248 | 0 | 0 | ||
Magna International Inc | Common Stock | 559222401 | 8,304 | 117,282 | SH | SOLE | 117,282 | 0 | 0 | ||
Peloton Interactive Inc | Common Stock | 70614W100 | 66,936 | 441,179 | SH | SOLE | 441,179 | 0 | 0 | ||
Veeva Systems Inc | Common Stock | 922475108 | 82,391 | 302,629 | SH | SOLE | 302,629 | 0 | 0 |