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Condensed Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Accumulated Other Comprehensive Income (Loss)
Total
Balance at Dec. 31, 2020 $ 2 $ 242,780 $ (160,731) $ (112) $ 81,939
Balance (in shares) at Dec. 31, 2020 22,493,661        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock $ 1 74,386     74,387
Issuance of common stock (in shares) 3,450,000        
Exercise of options for common stock issued under Equity Incentive Plan   67     67
Exercise of options for common stock issued under Equity Incentive Plan (in shares) 37,400        
Exercise of options for common stock not yet issued   (1)     (1)
Exercise of options for common stock not yet issued (in shares) (465)        
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 1,988        
Exercise of warrants of common stock   69     69
Exercise of warrants of common stock (in shares) 27,855        
Stock-based compensation expense   2,981     2,981
Net loss     (24,179)   (24,179)
Other comprehensive income (loss)       (42) (42)
Balance at Mar. 31, 2021 $ 3 320,282 (184,910) (154) 135,221
Balance (in shares) at Mar. 31, 2021 26,010,439        
Balance at Dec. 31, 2020 $ 2 242,780 (160,731) (112) 81,939
Balance (in shares) at Dec. 31, 2020 22,493,661        
Increase (Decrease) in Stockholders' Equity          
Net loss         (78,425)
Balance at Sep. 30, 2021 $ 3 326,108 (239,156) (254) 86,701
Balance (in shares) at Sep. 30, 2021 26,214,399        
Balance at Mar. 31, 2021 $ 3 320,282 (184,910) (154) 135,221
Balance (in shares) at Mar. 31, 2021 26,010,439        
Increase (Decrease) in Stockholders' Equity          
Secondary public offering issuance costs   35     35
Issuance of common stock for options exercised in prior periods under Equity Incentive Plan   1     1
Issuance of common stock for options exercised in prior periods under Equity Incentive Plan (in shares) 465        
Exercise of options for common stock issued under Equity Incentive Plan   341     341
Exercise of options for common stock issued under Equity Incentive Plan (in shares) 82,668        
Exercise of options for common stock not yet issued   (1)     (1)
Exercise of options for common stock not yet issued (in shares) (920)        
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 37,884        
Stock-based compensation expense   2,702     2,702
Net loss     (25,828)   (25,828)
Other comprehensive income (loss)       (31) (31)
Balance at Jun. 30, 2021 $ 3 323,360 (210,738) (185) 112,440
Balance (in shares) at Jun. 30, 2021 26,130,536        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock for options exercised in prior periods under Equity Incentive Plan   1     1
Issuance of common stock for options exercised in prior periods under Equity Incentive Plan (in shares) 920        
Exercise of options for common stock issued under Equity Incentive Plan   103     103
Exercise of options for common stock issued under Equity Incentive Plan (in shares) 70,368        
Exercise of options for common stock not yet issued   (1)     (1)
Exercise of options for common stock not yet issued (in shares) (115)        
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 12,690        
Stock-based compensation expense   2,645     2,645
Net loss     (28,418)   (28,418)
Other comprehensive income (loss)       (69) (69)
Balance at Sep. 30, 2021 $ 3 326,108 (239,156) (254) 86,701
Balance (in shares) at Sep. 30, 2021 26,214,399        
Balance at Dec. 31, 2021 $ 3 328,958 (266,315) (107) 62,539
Balance (in shares) at Dec. 31, 2021 26,215,514        
Increase (Decrease) in Stockholders' Equity          
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 21,417        
Restricted Stock Units released for common stock not yet issued (in shares) (21,417)        
Stock-based compensation expense   2,077     2,077
Issuance of options in-lieu of bonus   441     441
Net loss     (23,121)   (23,121)
Other comprehensive income (loss)       27 27
Balance at Mar. 31, 2022 $ 3 331,476 (289,436) (80) 41,963
Balance (in shares) at Mar. 31, 2022 26,215,514        
Balance at Dec. 31, 2021 $ 3 328,958 (266,315) (107) $ 62,539
Balance (in shares) at Dec. 31, 2021 26,215,514        
Increase (Decrease) in Stockholders' Equity          
Exercise of options for common stock issued under Equity Incentive Plan (in shares)         47,602
Net loss         $ (68,079)
Balance at Sep. 30, 2022 $ 5 343,995 (334,394) 23 9,629
Balance (in shares) at Sep. 30, 2022 48,058,956        
Balance at Mar. 31, 2022 $ 3 331,476 (289,436) (80) 41,963
Balance (in shares) at Mar. 31, 2022 26,215,514        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock, pre-funded warrants, and common warrants sold for cash, net of issuance costs $ 2 5,966     5,968
Issuance of common stock, pre-funded warrants, and common warrants sold for cash, net of issuance costs (in shares) 20,000,000        
Exercise of prefunded warrants for common stock   1,417     1,417
Exercise of prefunded warrants for common stock (in shares) 1,750,000        
Exercise of prefunded warrants for common stock not yet issued (in shares) (1,750,000)        
Issuance of common stock for Restricted Stock released in prior periods under Equity Incentive Plan (in shares) 21,417        
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 16,593        
Stock-based compensation expense   2,231     2,231
Net loss     (25,857)   (25,857)
Other comprehensive income (loss)       86 86
Balance at Jun. 30, 2022 $ 5 341,090 (315,293) 6 25,808
Balance (in shares) at Jun. 30, 2022 46,253,524        
Increase (Decrease) in Stockholders' Equity          
Issuance of common stock for pre-funded warrants exercised in prior periods (in shares) 1,750,000        
Exercise of options for common stock issued under Equity Incentive Plan   49     49
Exercise of options for common stock issued under Equity Incentive Plan (in shares) 47,602        
Restricted Stock Units released for common stock issued under Equity Incentive Plan (in shares) 7,830        
Stock-based compensation expense   2,856     2,856
Net loss     (19,101)   (19,101)
Other comprehensive income (loss)       17 17
Balance at Sep. 30, 2022 $ 5 $ 343,995 $ (334,394) $ 23 $ 9,629
Balance (in shares) at Sep. 30, 2022 48,058,956