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LICENSE AGREEMENT - Columbia (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 72 Months Ended
Jul. 15, 2022
Oct. 03, 2019
Mar. 31, 2019
Jan. 31, 2019
Oct. 31, 2016
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Dec. 31, 2021
Agreements                      
Research and development           $ 13,116 $ 17,597 $ 43,542 $ 46,846    
General and administrative           6,240 10,833 20,436 31,658    
Operating expenses           19,356 28,430 63,978 78,504    
Accrued expenses and other current liabilities           14,332   14,332   $ 14,332 $ 16,559
Accounts payable           6,973   6,973   6,973 9,461
Columbia University                      
Agreements                      
Research and development           0 0 0 0    
General and administrative           100 $ 46 200 $ 200    
Operating expenses                   2,600  
Accrued expenses and other current liabilities           100   100   100 12
Accounts payable           $ 0   $ 0   $ 0 $ 100
2016 license agreement | Columbia University                      
Agreements                      
Percentage of outstanding common stock issued         5.00%            
Fair value of stock issued         $ 500            
Written notice period for termination of agreement         90 days            
Written notice period for termination of agreement, uncured material breach         30 days            
Extended written notice period for termination of agreement, attempt to cure material breach         90 days            
2016 license agreement | Columbia University | Minimum                      
Agreements                      
Percentage of sublicensing revenue, if sublicenses rights granted         10.00%            
2016 license agreement | Columbia University | Maximum                      
Agreements                      
Payment on achievement of specified development and regulatory milestones         $ 1,300            
Payment on achievement of specified level of aggregate annual net sales         $ 1,000            
Percentage of sublicensing revenue, if sublicenses rights granted         20.00%            
2019 license agreement | Columbia University                      
Agreements                      
Period within which termination of agreement will become effective 90 days                    
2019 license agreement | Columbia University | Maximum                      
Agreements                      
Payment on achievement of specified development and regulatory milestones       $ 1,300              
Payment on achievement of specified level of aggregate annual net sales       $ 1,000              
2019 research agreement | Columbia University                      
Agreements                      
Agreement term     12 months                
P13k Research agreement | Columbia University                      
Agreements                      
Agreement term   18 months