X0508 4 2023-12-01 0 0001697532 Applied Therapeutics Inc. APLT 0001775404 Kanter Stacy J. C/O APPLIED THERAPEUTICS, INC. 545 FIFTH AVENUE, SUITE 1400 NEW YORK NY 10017 1 0 0 0 0 Common Stock 2023-12-01 4 P 0 30000 2.1789 A 63000 D Weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.1489 to $2.180 inclusive. The reporting person undertakes to provide the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above. /s/ Stacy J. Kanter 2023-12-05