X0306 4 2020-06-08 0 0001604821 Natera, Inc. NTRA 0001697362 Brophy Michael Burkes C/O NATERA, INC., 201 INDUSTRIAL ROAD SUITE 410 SAN CARLOS CA 94070 0 1 0 0 Chief Financial Officer Common Stock 2020-06-08 4 M 0 25000 A 48274 D Common Stock 2020-06-09 4 S 0 9076 39.5750 D 39198 D Common Stock 2020-06-09 4 M 0 3021 A 42219 D Common Stock 2020-06-10 4 S 0 1197 42.19 D 41022 D Restricted Stock Units 2029-06-08 4 M 0 25000 0 D Common Stock 25000 50000 D Restricted Stock Unit 2020-06-09 4 M 0 3021 0 D Common Stock 3021 21146 D Represents the partial vesting and settlement of Restricted Stock Units ("RSUs"), starting September 19, 2019. Each RSU represents a contingent right to receive one share of the common stock of the issuer. The sale of shares was effected in order to satisfy tax liabilities due at the time of vesting. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.56 to $39.9838 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Represents the partial vesting and settlement of RSUs, starting March 9, 2019. On March 22, 2019, the Reporting Person was granted RSUs covering 100,000 shares of common stock, which vests in tranches upon the Reporting Person achieving certain milestones relating to a combination of the passage of time and the Reporting Person achieving certain milestones relating to the Issuer's stock price, based on the average closing price per share of the Issuer's common stock for a calendar month, calculated as of the last day of such calendar month. On June 8, 2020, the criteria was satisfied for the vesting of RSUs covering 25,000 shares of common stock. The RSUs vest over four years. 25% of the RSUs vest on March 9, 2019 and the remaining shares vest in 12 equal quarterly installments thereafter. /s/ Tami Chen, attorney-in-fact 2020-06-10