908 DEVICES INC COM 65443P102 2151134 130768 SH SOLE 130768 0 0 AADI BIOSCIENCE INC COM 00032Q104 1440101 101918 SH SOLE 101918 0 0 ABIOMED INC COM 003654100 13012610 52970 SH SOLE 52970 0 0 AC IMMUNE SA SHS H00263105 393701 124589 SH SOLE 124589 0 0 AERIE PHARMACEUTICALS INC COM 00771V108 3877653 256289 SH SOLE 256289 0 0 AFFIMED N V COM N01045108 3889278 1887999 SH SOLE 1887999 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 2615878 21521 SH SOLE 21521 0 0 AMARIN CORP PLC SPONS ADR NEW 023111206 13039391 11962744 SH SOLE 11962744 0 0 AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 9475440 4690812 SH SOLE 4690812 0 0 ARGENX SE SPONSORED ADR 04016X101 1236381 3502 SH SOLE 3502 0 0 AVANTOR INC COM 05352A100 1459259 74452 SH SOLE 74452 0 0 BIOGEN INC COM 09062X103 16058448 60144 SH SOLE 60144 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 96316303 637139 SH SOLE 637139 0 0 BOLT BIOTHERAPEUTICS INC COM 097702104 46135 31172 SH SOLE 31172 0 0 CABALETTA BIO INC COM 12674W109 364359 560466 SH SOLE 560466 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 17607317 626372 SH SOLE 626372 0 0 CENTENE CORP DEL COM 15135B101 14885675 191308 SH SOLE 191308 0 0 COMMUNITY HEALTH SYS INC NEW COM 203668108 19009449 8841604 SH SOLE 8841604 0 0 DANAHER CORPORATION COM 235851102 42023962 162546 SH SOLE 162546 0 0 ELEDON PHARMACEUTICALS INC COM 28617K101 186971 67743 SH SOLE 67743 0 0 ELEVANCE HEALTH INC COM 036752103 15008090 33040 SH SOLE 33040 0 0 ENVISTA HOLDINGS CORPORATION COM 29415F104 20768763 633001 SH SOLE 633001 0 0 FATE THERAPEUTICS INC COM 31189P102 3172315 141558 SH SOLE 141558 0 0 GLYCOMIMETICS INC COM 38000Q102 55489 100579 SH SOLE 100579 0 0 GOSSAMER BIO INC COM 38341P102 6570203 548431 SH SOLE 548431 0 0 GSK PLC SPONSORED AD 37733W204 87268411 2939070 SH SOLE 2939070 0 0 GUARDANT HEALTH INC COM 40131M109 9230822 171481 SH SOLE 171481 0 0 HESKA CORP COM RESTRC NEW 42805E306 506284 6943 SH SOLE 6943 0 0 HORIZON THERAPEUTICS PUB L SHS G46188101 78574987 1269591 SH SOLE 1269591 0 0 HUMANA INC COM 444859102 11941029 24572 SH SOLE 24572 0 0 ICON PLC SHS G4705A100 1876761 10212 SH SOLE 10212 0 0 ILLUMINA INC COM 452327109 20414912 107002 SH SOLE 107002 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 1710390 9125 SH SOLE 9125 0 0 IONIS PHARMACEUTICALS INC COM 462222100 8927074 201833 SH SOLE 201833 0 0 IQVIA HLDGS INC COM 46266C105 1502919 8297 SH SOLE 8297 0 0 LABORATORY CORP AMER HLDGS COM NEW 50540R409 1481391 7233 SH SOLE 7233 0 0 LANTHEUS HLDGS INC COM 516544103 14550785 206893 SH SOLE 206893 0 0 LIQUIDIA CORPORATION COM NEW 53635D202 7623850 1401443 SH SOLE 1401443 0 0 MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 4084800 160000 SH SOLE 160000 0 0 MERUS N V COM N5749R100 5541760 276673 SH SOLE 276673 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 1165531 126826 SH SOLE 126826 0 0 NATERA INC COM 632307104 62469880 1425602 SH SOLE 1425602 0 0 PERKINELMER INC COM 714046109 1315207 10930 SH SOLE 10930 0 0 PLIANT THERAPEUTICS INC COM 729139105 6143812 294103 SH SOLE 294103 0 0 POINT BIOPHARMA GLOBAL INC COM 730541109 3169702 410052 SH SOLE 410052 0 0 PUMA BIOTECHNOLOGY INC COM 74587V107 3568521 1505705 SH SOLE 1505705 0 0 REPLIGEN CORP COM 759916109 681268 3641 SH SOLE 3641 0 0 SANOFI SPONSORED ADR 80105N105 37869251 996035 SH SOLE 996035 0 0 SERES THERAPEUTICS INC COM 81750R102 12427997 1935825 SH SOLE 1935825 0 0 SONIDA SENIOR LIVING INC COM 140475203 191486 11791 SH SOLE 11791 0 0 SPDR SER TR S&P BIOTECH 78464A870 7932000 100000 SH SOLE 100000 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 29110759 1211434 SH SOLE 1211434 0 0 TARO PHARMACEUTICAL INDS LTD SHS M8737E108 6697022 223383 SH SOLE 223383 0 0 TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 32787885 4062935 SH SOLE 4062935 0 0 THIRD HARMONIC BIO INC CO 88427A107 189700 10000 SH SOLE 10000 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 53439220 255226 SH SOLE 255226 0 0 VERA THERAPEUTICS INC CL A 92337R101 3327109 156129 SH SOLE 156129 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 9811717 478387 SH SOLE 478387 0 0 XENON PHARMACEUTICALS INC COM 98420N105 9371993 259612 SH SOLE 259612 0 0 XOMA CORP DEL COM NEW 98419J206 1583280 88402 SH SOLE 88402 0 0 AMN HEALTHCARE SVCS INC COM 001744101 2013240 19000 SH Put SOLE 19000 0 0 BIOGEN INC COM 09062X103 9905700 37100 SH Call SOLE 37100 0 0 BIOGEN INC COM 09062X103 13350000 50000 SH Put SOLE 50000 0 0 MERCK & CO INC COM 58933Y105 4194044 48700 SH Call SOLE 48700 0 0 MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 612720 24000 SH Call SOLE 24000 0 0 INVESCO QQQ TR UNIT SER 1 46090E103 208917142 781700 SH Put SOLE 781700 0 0 TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 2202303 272900 SH Call SOLE 272900 0 0 SPDR SER TR S&P BIOTECH 78464A870 7138800 90000 SH Call SOLE 90000 0 0 GSK PLC SPONSORED AD 37733W204 61617591 2093700 SH Call SOLE 2093700 0 0