The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
908 DEVICES INC COM 65443P102   4,128,002 217,149 SH   SOLE   217,149 0 0
AADI BIOSCIENCE INC COM 00032Q104   2,559,364 150,817 SH   SOLE   150,817 0 0
AC IMMUNE SA SHS H00263105   498,356 124,589 SH   SOLE   124,589 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107   488,397 237,086 SH   SOLE   237,086 0 0
AGILENT TECHNOLOGIES INC COM 00846U101   2,548,014 19,255 SH   SOLE   19,255 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   8,633,306 52,871 SH   SOLE   52,871 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   29,544,677 8,980,145 SH   SOLE   8,980,145 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105   22,899,542 5,491,497 SH   SOLE   5,491,497 0 0
ANAPTYSBIO INC COM 032724106   2,824,442 114,165 SH   SOLE   114,165 0 0
ANTHEM INC COM 036752103   15,940,580 32,451 SH   SOLE   32,451 0 0
ARGENX SE SPONSORED ADR 04016X101   7,296,904 23,142 SH   SOLE   23,142 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302   21,610,341 470,506 SH   SOLE   470,506 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   48,959,306 417,172 SH   SOLE   417,172 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108   576,800 280,000 SH   SOLE   280,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   49,440,747 745,263 SH   SOLE   745,263 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   1,549,322 371,540 SH   SOLE   371,540 0 0
AVANTOR INC COM 05352A100   33,658,746 995,232 SH   SOLE   995,232 0 0
AVROBIO INC COM 05455M100   389,887 295,369 SH   SOLE   295,369 0 0
BIO-TECHNE CORP COM 09073M104   459,888 1,062 SH   SOLE   1,062 0 0
BIOGEN INC COM 09062X103   16,427,432 78,003 SH   SOLE   78,003 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105   76,438,048 644,666 SH   SOLE   644,666 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   21,677,589 636,453 SH   SOLE   636,453 0 0
CENTENE CORP DEL COM 15135B101   10,032,922 119,170 SH   SOLE   119,170 0 0
CLOVIS ONCOLOGY INC COM 189464100   60,600 30,000 SH   SOLE   30,000 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108   84,594,060 7,126,711 SH   SOLE   7,126,711 0 0
CYCLERION THERAPEUTICS INC COM 23255M105   412,870 371,955 SH   SOLE   371,955 0 0
DANAHER CORPORATION COM 235851102   46,903,529 159,768 SH   SOLE   159,768 0 0
DEXCOM INC COM 252131107   14,531,486 28,404 SH   SOLE   28,404 0 0
ELEDON PHARMACEUTICALS INC COM 28617K101   449,192 114,008 SH   SOLE   114,008 0 0
ENSIGN GROUP INC COM 29358P101   936,406 10,397 SH   SOLE   10,397 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104   27,733,087 569,351 SH   SOLE   569,351 0 0
EXELIXIS INC COM 30161Q104   4,605,547 203,156 SH   SOLE   203,156 0 0
FATE THERAPEUTICS INC COM 31189P102   17,681,407 456,059 SH   SOLE   456,059 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   55,533,447 1,259,162 SH   SOLE   1,259,162 0 0
GLYCOMIMETICS INC COM 38000Q102   114,660 100,579 SH   SOLE   100,579 0 0
GOSSAMER BIO INC COM 38341P102   3,252,596 374,723 SH   SOLE   374,723 0 0
GUARDANT HEALTH INC COM 40131M109   14,122,567 213,203 SH   SOLE   213,203 0 0
HCA HEALTHCARE INC COM 40412C101   27,929,093 111,440 SH   SOLE   111,440 0 0
HEALTHEQUITY INC COM 42226A107   9,720,802 144,140 SH   SOLE   144,140 0 0
HESKA CORP COM RESTRC NEW 42805E306   807,002 5,836 SH   SOLE   5,836 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101   64,171,682 609,939 SH   SOLE   609,939 0 0
ICON PLC SHS G4705A100   11,386,588 46,816 SH   SOLE   46,816 0 0
ILLUMINA INC COM 452327109   13,542,395 38,759 SH   SOLE   38,759 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   2,462,614 8,163 SH   SOLE   8,163 0 0
IONIS PHARMACEUTICALS INC COM 462222100   5,882,174 158,806 SH   SOLE   158,806 0 0
IQVIA HLDGS INC COM 46266C105   13,773,180 59,570 SH   SOLE   59,570 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106   4,259,091 27,047 SH   SOLE   27,047 0 0
KARUNA THERAPEUTICS INC COM 48576A100   2,020,272 15,934 SH   SOLE   15,934 0 0
KODIAK SCIENCES INC COM 50015M109   704,064 91,200 SH   SOLE   91,200 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409   9,995,351 37,910 SH   SOLE   37,910 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   9,890,378 1,377,490 SH   SOLE   1,377,490 0 0
MASIMO CORP COM 574795100   30,413,494 208,970 SH   SOLE   208,970 0 0
MCKESSON CORP COM 58155Q103   16,071,892 52,375 SH   SOLE   52,375 0 0
MERCK & CO INC COM 58933Y105   1,986,583 9,483 SH   SOLE   9,483 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107   414,590 370,170 SH   SOLE   370,170 0 0
MERUS N V COM N5749R100   2,031,888 76,849 SH   SOLE   76,849 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   944,799 147,165 SH   SOLE   147,165 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109   9,754,151 280,695 SH   SOLE   280,695 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101   298,742 419,581 SH   SOLE   419,581 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107   8,304,801 445,059 SH   SOLE   445,059 0 0
PERKINELMER INC COM 714046109   1,707,614 9,788 SH   SOLE   9,788 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107   4,102,992 1,424,650 SH   SOLE   1,424,650 0 0
QIAGEN NV SHS NEW N72482123   9,442,251 192,699 SH   SOLE   192,699 0 0
R1 RCM INC COM 749397105   36,433,901 1,361,506 SH   SOLE   1,361,506 0 0
RADIUS HEALTH INC COM NEW 750469207   2,668,179 302,172 SH   SOLE   302,172 0 0
REPLIGEN CORP COM 759916109   6,869,235 36,521 SH   SOLE   36,521 0 0
SONIDA SENIOR LIVING INC COM 140475203   503,874 15,209 SH   SOLE   15,209 0 0
SPERO THERAPEUTICS INC COM 84833T103   518,859 59,639 SH   SOLE   59,639 0 0
SURGALIGN HOLDINGS INC COM 86882C105   478,908 1,573,802 SH   SOLE   1,573,802 0 0
SYNEOS HEALTH INC CL A 87166B102   6,590,625 81,416 SH   SOLE   81,416 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108   9,529,572 220,286 SH   SOLE   220,286 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   38,908,423 4,143,602 SH   SOLE   4,143,602 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   52,429,702 292,234 SH   SOLE   292,234 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   2,879,688 155,743 SH   SOLE   155,743 0 0
XENON PHARMACEUTICALS INC COM 98420N105   12,534,342 410,021 SH   SOLE   410,021 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107   4,622,628 100,187 SH   SOLE   100,187 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   37,966,382 572,300 SH Call SOLE   572,300 0 0
BIOGEN INC COM 09062X103   29,484,000 140,000 SH Call SOLE   140,000 0 0
ISHARES INC MSCI TAIWAN ETF 46434G772   6,145,000 100,000 SH Put SOLE   100,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   67,679,172 1,553,700 SH Call SOLE   1,553,700 0 0
ISHARES TR RUS 2000 GRW ETF 464287648   434,775 1,700 SH Put SOLE   1,700 0 0
KODIAK SCIENCES INC COM 50015M109   1,398,864 181,200 SH Put SOLE   181,200 0 0
MERCK & CO INC COM 58933Y105   3,995,835 48,700 SH Call SOLE   48,700 0 0
PROGYNY INC COM 74340E103   2,570,000 50,000 SH Put SOLE   50,000 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   65,257,200 180,000 SH Put SOLE   180,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   872,331 92,900 SH Call SOLE   92,900 0 0