The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AC IMMUNE SA SHS H00263105   1,487,936 221,749 SH   SOLE   221,749 0 0
ACCELERON PHARMA INC COM 00434H108   60,147,917 349,494 SH   SOLE   349,494 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107   2,300,066 444,887 SH   SOLE   444,887 0 0
AGILENT TECHNOLOGIES INC COM 00846U101   2,939,510 18,660 SH   SOLE   18,660 0 0
AKOYA BIOSCIENCES INC COM 00974H104   1,278,289 91,568 SH   SOLE   91,568 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   11,183,783 59,233 SH   SOLE   59,233 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   59,185,449 11,604,990 SH   SOLE   11,604,990 0 0
AMN HEALTHCARE SVCS INC COM 001744101   1,147,500 10,000 SH   SOLE   10,000 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105   36,578,114 6,849,834 SH   SOLE   6,849,834 0 0
ANAPTYSBIO INC COM 032724106   2,116,824 78,054 SH   SOLE   78,054 0 0
ANTHEM INC COM 036752103   11,790,918 31,628 SH   SOLE   31,628 0 0
ARGENX SE SPONSORED ADR 04016X101   1,735,292 5,746 SH   SOLE   5,746 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302   51,519,515 689,501 SH   SOLE   689,501 0 0
ARK ETF TR INNOVATION ETF 00214Q104   3,868,550 35,000 SH   SOLE   35,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   70,960,906 445,203 SH   SOLE   445,203 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108   1,218,000 350,000 SH   SOLE   350,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   53,501,928 890,808 SH   SOLE   890,808 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   2,607,385 398,074 SH   SOLE   398,074 0 0
AVANTOR INC COM 05352A100   52,843,373 1,292,014 SH   SOLE   1,292,014 0 0
AVROBIO INC COM 05455M100   2,005,898 359,480 SH   SOLE   359,480 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108   27,791,346 464,801 SH   SOLE   464,801 0 0
CATALENT INC COM 148806102   24,524,668 184,299 SH   SOLE   184,299 0 0
CENTENE CORP DEL COM 15135B101   8,792,377 141,107 SH   SOLE   141,107 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108   70,061,507 5,988,163 SH   SOLE   5,988,163 0 0
CROSS CTRY HEALTHCARE INC COM 227483104   424,800 20,000 SH   SOLE   20,000 0 0
CYCLERION THERAPEUTICS INC COM 23255M105   1,141,902 371,955 SH   SOLE   371,955 0 0
DANAHER CORPORATION COM 235851102   45,068,183 147,938 SH   SOLE   147,938 0 0
DEXCOM INC COM 252131107   3,500,451 6,401 SH   SOLE   6,401 0 0
ELEDON PHARMACEUTICALS INC COM 28617K101   704,569 114,008 SH   SOLE   114,008 0 0
ENSIGN GROUP INC COM 29358P101   779,177 10,397 SH   SOLE   10,397 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104   33,902,935 810,881 SH   SOLE   810,881 0 0
EVOLENT HEALTH INC CL A 30050B101   3,105,270 100,170 SH   SOLE   100,170 0 0
EXELIXIS INC COM 30161Q104   10,914,730 516,307 SH   SOLE   516,307 0 0
F-STAR THERAPEUTICS INC COM 30315R107   365,510 49,933 SH   SOLE   49,933 0 0
FATE THERAPEUTICS INC COM 31189P102   15,463,247 260,895 SH   SOLE   260,895 0 0
FREQUENCY THERAPEUTICS INC COM 35803L108   211,800 30,000 SH   SOLE   30,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   15,410,002 401,654 SH   SOLE   401,654 0 0
GOHEALTH INC COM CL A 38046W105   6,346,467 1,261,723 SH   SOLE   1,261,723 0 0
GOSSAMER BIO INC COM 38341P102   1,884,369 149,910 SH   SOLE   149,910 0 0
GUARDANT HEALTH INC COM 40131M109   12,546,129 100,361 SH   SOLE   100,361 0 0
HCA HEALTHCARE INC COM 40412C101   9,312,196 38,366 SH   SOLE   38,366 0 0
HEALTHEQUITY INC COM 42226A107   7,407,119 114,378 SH   SOLE   114,378 0 0
HEALTHSTREAM INC COM 42222N103   2,223,867 77,812 SH   SOLE   77,812 0 0
HESKA CORP COM RESTRC NEW 42805E306   1,169,894 4,525 SH   SOLE   4,525 0 0
HILL-ROM HLDGS INC COM 431475102   4,500,000 30,000 SH   SOLE   30,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101   69,521,752 634,670 SH   SOLE   634,670 0 0
HUMANA INC COM 444859102   9,390,507 24,083 SH   SOLE   24,083 0 0
ICON PLC SHS G4705A100   18,842,120 71,911 SH   SOLE   71,911 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   8,602,136 230,744 SH   SOLE   230,744 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   3,126,602 3,145 SH   SOLE   3,145 0 0
IONIS PHARMACEUTICALS INC COM 462222100   15,109,804 450,501 SH   SOLE   450,501 0 0
IQVIA HLDGS INC COM 46266C105   1,626,477 6,790 SH   SOLE   6,790 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106   6,667,290 113,854 SH   SOLE   113,854 0 0
KARUNA THERAPEUTICS INC COM 48576A100   3,058,250 25,000 SH   SOLE   25,000 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409   36,111,848 128,311 SH   SOLE   128,311 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302   4,197,658 872,694 SH   SOLE   872,694 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   2,564,175 929,049 SH   SOLE   929,049 0 0
LOGICBIO THERAPEUTICS INC COM 54142F102   1,602,629 349,919 SH   SOLE   349,919 0 0
MAGELLAN HEALTH INC COM NEW 559079207   9,899,385 104,700 SH   SOLE   104,700 0 0
MAGENTA THERAPEUTICS INC COM 55910K108   1,447,839 198,879 SH   SOLE   198,879 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107   16,088,915 327,810 SH   SOLE   327,810 0 0
MASIMO CORP COM 574795100   18,137,570 67,000 SH   SOLE   67,000 0 0
MCKESSON CORP COM 58155Q103   32,288,796 161,708 SH   SOLE   161,708 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107   2,176,957 899,569 SH   SOLE   899,569 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   648,639 113,597 SH   SOLE   113,597 0 0
MIRATI THERAPEUTICS INC COM 60468T105   1,654,993 9,355 SH   SOLE   9,355 0 0
MORPHIC HLDG INC COM 61775R105   2,469,504 43,600 SH   SOLE   43,600 0 0
MYOMO INC COM NEW 62857J201   1,783,500 150,000 SH   SOLE   150,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109   8,097,751 168,668 SH   SOLE   168,668 0 0
NATERA INC COM 632307104   12,502,342 112,189 SH   SOLE   112,189 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101   1,310,036 569,581 SH   SOLE   569,581 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107   16,908,941 914,986 SH   SOLE   914,986 0 0
OUTSET MED INC COM 690145107   2,348,400 47,500 SH   SOLE   47,500 0 0
PERKINELMER INC COM 714046109   8,158,666 47,081 SH   SOLE   47,081 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109   933,000 300,000 SH   SOLE   300,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107   2,789,559 397,940 SH   SOLE   397,940 0 0
QIAGEN NV SHS NEW N72482123   7,395,873 143,109 SH   SOLE   143,109 0 0
R1 RCM INC COM 749397105   16,832,808 764,780 SH   SOLE   764,780 0 0
REPLIGEN CORP COM 759916109   1,272,134 4,402 SH   SOLE   4,402 0 0
SANOFI SPONSORED ADR 80105N105   12,492,561 259,128 SH   SOLE   259,128 0 0
SI-BONE INC COM 825704109   3,213,000 150,000 SH   SOLE   150,000 0 0
SURGALIGN HOLDINGS INC COM 86882C105   3,824,304 3,508,536 SH   SOLE   3,508,536 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108   11,413,059 179,366 SH   SOLE   179,366 0 0
TELIGENT INC NEW COM NEW 87960W203   426,717 1,069,465 SH   SOLE   1,069,465 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   34,623,791 3,554,804 SH   SOLE   3,554,804 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   82,040,457 444,471 SH   SOLE   444,471 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   2,632,000 160,000 SH   SOLE   160,000 0 0
ZOGENIX INC COM NEW 98978L204   11,766,037 774,591 SH   SOLE   774,591 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   4,166,144 126,400 SH Call SOLE   126,400 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   15,633,618 260,300 SH Call SOLE   260,300 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108   12,603,240 1,077,200 SH Call SOLE   1,077,200 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   635,426 18,700 SH Call SOLE   18,700 0 0
EDITAS MEDICINE INC COM 28106W103   2,054,000 50,000 SH Put SOLE   50,000 0 0
FREQUENCY THERAPEUTICS INC COM 35803L108   479,374 67,900 SH Put SOLE   67,900 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   57,456,377 1,503,700 SH Call SOLE   1,503,700 0 0
HILL-ROM HLDGS INC COM 431475102   4,410,000 29,400 SH Call SOLE   29,400 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101   7,667,800 70,000 SH Call SOLE   70,000 0 0
MERCK & CO INC COM 58933Y105   3,657,857 48,700 SH Call SOLE   48,700 0 0
NOVAVAX INC COM NEW 670002401   2,073,100 10,000 SH Call SOLE   10,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   42,914,000 100,000 SH Put SOLE   100,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   9,373,776 962,400 SH Call SOLE   962,400 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   31,434,887 173,300 SH Call SOLE   173,300 0 0