The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108   42,044,797 335,045 SH   SOLE   335,045 0 0
AFFIMED N V COM N01045108   4,819,007 566,942 SH   SOLE   566,942 0 0
AGILENT TECHNOLOGIES INC COM 00846U101   2,255,728 15,261 SH   SOLE   15,261 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   8,668,575 51,136 SH   SOLE   51,136 0 0
ALPHA HEALTHCARE ACQUISTN CO CL A 020751103   2,089,215 205,026 SH   SOLE   205,026 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   73,012,283 16,669,471 SH   SOLE   16,669,471 0 0
AMN HEALTHCARE SVCS INC COM 001744101   15,429,615 159,101 SH   SOLE   159,101 0 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105   28,798,592 5,624,725 SH   SOLE   5,624,725 0 0
ANTHEM INC COM 036752103   3,868,398 10,132 SH   SOLE   10,132 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302   71,546,900 773,480 SH   SOLE   773,480 0 0
ARK ETF TR INNOVATION ETF 00214Q104   11,116,300 85,000 SH   SOLE   85,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   31,805,370 241,774 SH   SOLE   241,774 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   59,044,748 985,722 SH   SOLE   985,722 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   3,141,211 473,074 SH   SOLE   473,074 0 0
AVANTOR INC COM 05352A100   34,609,360 974,637 SH   SOLE   974,637 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108   31,961,877 478,328 SH   SOLE   478,328 0 0
CENTENE CORP DEL COM 15135B101   4,959,240 68,000 SH   SOLE   68,000 0 0
CENTURY THERAPEUTICS INC COM 15673T100   2,960,435 100,901 SH   SOLE   100,901 0 0
CIGNA CORP NEW COM 125523100   9,896,487 41,745 SH   SOLE   41,745 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108   59,007,496 3,821,729 SH   SOLE   3,821,729 0 0
CROSS CTRY HEALTHCARE INC COM 227483104   508,673 30,810 SH   SOLE   30,810 0 0
CULLINAN ONCOLOGY INC COM 230031106   4,219,910 163,880 SH   SOLE   163,880 0 0
DANAHER CORPORATION COM 235851102   54,975,987 204,705 SH   SOLE   204,705 0 0
DEXCOM INC COM 252131107   4,067,175 9,525 SH   SOLE   9,525 0 0
ENSIGN GROUP INC COM 29358P101   778,161 8,973 SH   SOLE   8,973 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104   28,349,995 656,098 SH   SOLE   656,098 0 0
EXELIXIS INC COM 30161Q104   3,279,600 180,000 SH   SOLE   180,000 0 0
F-STAR THERAPEUTICS INC COM 30315R107   859,000 100,000 SH   SOLE   100,000 0 0
FATE THERAPEUTICS INC COM 31189P102   30,059,456 346,347 SH   SOLE   346,347 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   4,613,279 112,679 SH   SOLE   112,679 0 0
GOHEALTH INC COM CL A 38046W105   772,358 68,899 SH   SOLE   68,899 0 0
GUARDANT HEALTH INC COM 40131M109   224,660 1,809 SH   SOLE   1,809 0 0
HCA HEALTHCARE INC COM 40412C101   1,718,836 8,314 SH   SOLE   8,314 0 0
HEALTHEQUITY INC COM 42226A107   15,894,800 197,500 SH   SOLE   197,500 0 0
HEALTHSTREAM INC COM 42222N103   2,174,067 77,812 SH   SOLE   77,812 0 0
HESKA CORP COM RESTRC NEW 42805E306   783,839 3,412 SH   SOLE   3,412 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101   62,433,346 666,738 SH   SOLE   666,738 0 0
HUMANA INC COM 444859102   8,272,025 18,656 SH   SOLE   18,656 0 0
IMMUNOVANT INC COM 45258J102   1,164,634 110,183 SH   SOLE   110,183 0 0
INTERSECT ENT INC COM 46071F103   2,997,398 175,389 SH   SOLE   175,389 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   4,794,799 117,462 SH   SOLE   117,462 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   2,375,430 2,583 SH   SOLE   2,583 0 0
IONIS PHARMACEUTICALS INC COM 462222100   17,631,380 442,000 SH   SOLE   442,000 0 0
IQVIA HLDGS INC COM 46266C105   1,384,132 5,712 SH   SOLE   5,712 0 0
KADMON HLDGS INC COM 48283N106   3,463,631 894,995 SH   SOLE   894,995 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302   1,052,437 229,289 SH   SOLE   229,289 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   2,800,080 979,049 SH   SOLE   979,049 0 0
MAGELLAN HEALTH INC COM NEW 559079207   9,862,740 104,700 SH   SOLE   104,700 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107   3,129,750 75,000 SH   SOLE   75,000 0 0
MCKESSON CORP COM 58155Q103   14,373,387 75,000 SH   SOLE   75,000 0 0
NATERA INC COM 632307104   1,057,418 9,314 SH   SOLE   9,314 0 0
OCULAR THERAPEUTIX INC COM 67576A100   2,127,000 150,000 SH   SOLE   150,000 0 0
OMNICELL COM COM 68213N109   14,897,531 98,366 SH   SOLE   98,366 0 0
OPTION CARE HEALTH INC COM NEW 68404L201   6,326,925 289,297 SH   SOLE   289,297 0 0
ORGANON & CO COMMON STOCK 68622V106   21,172,801 699,696 SH   SOLE   699,696 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107   29,851,620 1,394,284 SH   SOLE   1,394,284 0 0
OUTSET MED INC COM 690145107   5,362,854 107,300 SH   SOLE   107,300 0 0
QIAGEN NV SHS NEW N72482123   31,497,073 651,035 SH   SOLE   651,035 0 0
R1 RCM INC COM 749397105   17,124,800 770,000 SH   SOLE   770,000 0 0
REPLIGEN CORP COM 759916109   736,997 3,692 SH   SOLE   3,692 0 0
SERES THERAPEUTICS INC COM 81750R102   1,420,506 59,560 SH   SOLE   59,560 0 0
SURGALIGN HOLDINGS INC COM 86882C105   4,906,258 3,882,096 SH   SOLE   3,882,096 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108   12,538,958 174,249 SH   SOLE   174,249 0 0
TELIGENT INC NEW COM NEW 87960W203   1,337,389 2,500,260 SH   SOLE   2,500,260 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   37,663,610 3,804,405 SH   SOLE   3,804,405 0 0
TG THERAPEUTICS INC COM 88322Q108   2,705,990 69,760 SH   SOLE   69,760 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   79,468,762 442,945 SH   SOLE   442,945 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   10,988,835 54,500 SH   SOLE   54,500 0 0
ZOGENIX INC COM NEW 98978L204   8,568,461 495,860 SH   SOLE   495,860 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   2,063,394 84,600 SH Call SOLE   84,600 0 0
ARK ETF TR GENOMIC REV ETF 00214Q302   18,407,500 199,000 SH Call SOLE   199,000 0 0
BIOGEN INC COM 09062X103   40,028,812 115,600 SH Call SOLE   115,600 0 0
BIOGEN INC COM 09062X103   692,540 2,000 SH Put SOLE   2,000 0 0
FREQUENCY THERAPEUTICS INC COM 35803L108   921,300 92,500 SH Put SOLE   92,500 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108   1,400,800 40,000 SH Put SOLE   40,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   55,895,334 1,403,700 SH Call SOLE   1,403,700 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101   6,554,800 70,000 SH Call SOLE   70,000 0 0
ISHARES TR TIPS BD ETF 464287176   8,960,700 70,000 SH Put SOLE   70,000 0 0
MERCK & CO INC COM 58933Y105   3,787,399 48,700 SH Call SOLE   48,700 0 0
NOVAVAX INC COM NEW 670002401   2,123,100 10,000 SH Call SOLE   10,000 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   88,607,500 250,000 SH Put SOLE   250,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   107,015,000 250,000 SH Put SOLE   250,000 0 0
TELADOC HEALTH INC COM 87918A105   6,651,600 40,000 SH Call SOLE   40,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   1,909,710 192,900 SH Call SOLE   192,900 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   34,942,479 173,300 SH Call SOLE   173,300 0 0
SPDR SER TR S&P BIOTECH 78464A870   27,080,000 200,000 SH Call SOLE   200,000 0 0
SPDR SER TR S&P BIOTECH 78464A870   13,540,000 100,000 SH Put SOLE   100,000 0 0