The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100   7,807,745 27,339 SH   SOLE   27,339 0 0
AERIE PHARMACEUTICALS INC COM 00771V108   5,452,003 114,779 SH   SOLE   114,779 0 0
AFFIMED N V COM N01045108   1,353,118 322,171 SH   SOLE   322,171 0 0
ALBIREO PHARMA INC COM 01345P106   580,714 18,029 SH   SOLE   18,029 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   42,771,558 2,060,287 SH   SOLE   2,060,287 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   2,034,806 104,349 SH   SOLE   104,349 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101   198,667 73,717 SH   SOLE   73,717 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607   3,394,572 75,721 SH   SOLE   75,721 0 0
ARGENX SE SPONSORED ADR 04016X101   4,910,457 39,334 SH   SOLE   39,334 0 0
ARQULE INC COM 04269E107   3,098,737 646,918 SH   SOLE   646,918 0 0
ARRAY BIOPHARMA INC COM 04269X105   5,220,051 214,112 SH   SOLE   214,112 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101   12,157,939 103,296 SH   SOLE   103,296 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103   3,360,811 412,876 SH   SOLE   412,876 0 0
BIOSCRIP INC COM 09069N108   246,022 123,011 SH   SOLE   123,011 0 0
CARETRUST REIT INC COM 14174T107   976,632 41,264 SH   SOLE   41,264 0 0
CENTENE CORP DEL COM 15135B101   1,253,160 23,600 SH   SOLE   23,600 0 0
COHERUS BIOSCIENCES INC COM 19249H103   1,637,291 120,036 SH   SOLE   120,036 0 0
CONCERT PHARMACEUTICALS INC COM 206022105   569,149 47,154 SH   SOLE   47,154 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   1,514,528 42,400 SH   SOLE   42,400 0 0
CYMABAY THERAPEUTICS INC COM 23257D103   1,424,891 107,296 SH   SOLE   107,296 0 0
DANAHER CORPORATION COM 235851102   20,985,459 158,764 SH   SOLE   158,764 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101   5,812,527 250,432 SH   SOLE   250,432 0 0
DERMIRA INC COM 24983L104   2,432,225 179,500 SH   SOLE   179,500 0 0
DICERNA PHARMACEUTICALS INC COM 253031108   601,734 41,074 SH   SOLE   41,074 0 0
EHEALTH INC COM 28238P109   12,508,459 200,649 SH   SOLE   200,649 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105   974,518 69,708 SH   SOLE   69,708 0 0
ENSIGN GROUP INC COM 29358P101   8,174,251 159,545 SH   SOLE   159,545 0 0
FATE THERAPEUTICS INC COM 31189P102   6,149,693 350,011 SH   SOLE   350,011 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105   1,104,975 294,660 SH   SOLE   294,660 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105   34,065,052 803,185 SH   SOLE   803,185 0 0
HESKA CORP COM RESTRC NEW 42805E306   568,602 6,680 SH   SOLE   6,680 0 0
INVACARE CORP COM 461203101   661,908 79,081 SH   SOLE   79,081 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108   2,647,835 195,701 SH   SOLE   195,701 0 0
MEDICINES CO COM 584688105   2,129,790 76,200 SH   SOLE   76,200 0 0
MYOKARDIA INC COM 62857M105   1,822,353 35,052 SH   SOLE   35,052 0 0
NUVASIVE INC COM 670704105   18,774,831 330,601 SH   SOLE   330,601 0 0
OTONOMY INC COM 68906L105   473,663 180,100 SH   SOLE   180,100 0 0
PFENEX INC COM 717071104   467,826 75,700 SH   SOLE   75,700 0 0
PTC THERAPEUTICS INC COM 69366J200   3,786,584 100,600 SH   SOLE   100,600 0 0
R1 RCM INC COM 749397105   28,658,583 2,963,659 SH   SOLE   2,963,659 0 0
RADIUS HEALTH INC COM NEW 750469207   12,869,615 645,417 SH   SOLE   645,417 0 0
SANOFI SPONSORED ADR 80105N105   14,718,761 332,402 SH   SOLE   332,402 0 0
SAREPTA THERAPEUTICS INC COM 803607100   9,961,185 83,574 SH   SOLE   83,574 0 0
TELIGENT INC NEW COM 87960W104   2,986,864 2,574,883 SH   SOLE   2,574,883 0 0
TG THERAPEUTICS INC COM 88322Q108   6,018,696 748,594 SH   SOLE   748,594 0 0
TRICIDA INC COM 89610F101   1,911,999 49,508 SH   SOLE   49,508 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   7,032,225 38,229 SH   SOLE   38,229 0 0
XENON PHARMACEUTICALS INC COM 98420N105   2,279,294 224,340 SH   SOLE   224,340 0 0
ZOGENIX INC COM NEW 98978L204   27,253,549 495,429 SH   SOLE   495,429 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108   4,899,468 43,800 SH Call SOLE   43,800 0 0
NOVAVAX INC COM 670002104   79,936 145,100 SH Put SOLE   145,100 0 0
CONCERT PHARMACEUTICALS INC COM 206022105   27,761 2,300 SH Call SOLE   2,300 0 0