<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2017-07-19</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001630472</issuerCik>
        <issuerName>TPG RE Finance Trust, Inc.</issuerName>
        <issuerTradingSymbol>TRTX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001696998</rptOwnerCik>
            <rptOwnerName>Coleman Matthew</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O TPG RE FINANCE TRUST, INC.,</rptOwnerStreet1>
            <rptOwnerStreet2>888 SEVENTH AVENUE, 35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10106</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Class A Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>4303</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Explanation of Responses</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">TPG RE Finance Trust Equity, L.P. (&quot;TPG RE Finance Trust Equity&quot;) directly holds 926,951 shares of Class A common stock (&quot;Class A Common Stock&quot;) of TPG RE Finance Trust, Inc. (the &quot;Issuer&quot;), including 4,303 shares of Class A Common Stock indirectly beneficially owned by Matthew Coleman (through his indirect limited partnership interest in TPG RE Finance Trust Equity).  The shares of Class A Common Stock reported herein include shares of Class A Common Stock to be received by TPG RE Finance Trust Equity upon payment of a stock dividend declared by the Issuer on July 3, 2017 with respect to holders of record on that date.</footnote>
        <footnote id="F2">Pursuant to the Articles of Amendment and Restatement of the Issuer, each share of Class A Common Stock is convertible at any time or from time to time, at the option of the holder, for one share of common stock (&quot;Common Stock&quot;) of the Issuer.</footnote>
        <footnote id="F3">Mr. Coleman is a TPG Partner.  TPG is affiliated with TPG Holdings III, L.P., TPG/NJ (RE) Partnership, L.P., TPG RE Finance Trust Management, L.P. and TPG RE Finance Trust Equity (collectively, the &quot;TPG Funds&quot;), which collectively beneficially own shares of Common Stock.</footnote>
        <footnote id="F4">Mr. Coleman disclaims beneficial ownership of all of the securities that are or may be beneficially owned by the TPG Funds or any of their affiliates.  Pursuant to Rule 16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the &quot;Exchange Act&quot;), this filing shall not be deemed an admission that Mr. Coleman is, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owner of any equity securities of the Issuer in excess of his pecuniary interest.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Matthew Coleman</signatureName>
        <signatureDate>2017-07-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
