The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 BBG00ZHF9WP3 71,126 78,169 SH   SOLE   78,169 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 BBG00VR8SF73 66,092 13,769 SH   SOLE   13,769 0 0
ANNEXON INC COM 03589W102 BBG007QVDFH1 74,766 31,680 SH   SOLE   31,680 0 0
ATHIRA PHARMA INC COM 04746L104 BBG00C77LXM0 42,040 20,810 SH   SOLE   20,810 0 0
BARCLAYS BANK PLC DJUBS CMDT ETN36 06738C778 BBG001SPJ625 1,703,549 53,004 SH   SOLE   53,004 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 BBG001V0GS49 63,754 49,421 SH   SOLE   49,421 0 0
DBX ETF TR XTRACK MSCI EAFE 233051200 BBG001S9Z3V8 5,896,890 168,963 SH   SOLE   168,963 0 0
DEERE & CO COM 244199105 BBG001S5QFF7 414,049 1,097 SH   SOLE   1,097 0 0
FIRST TR EXCHANGE-TRADED FD NO AMER ENERGY 33738D101 BBG0034YTRP6 4,875,691 184,544 SH   SOLE   184,544 0 0
FLEXSHARES TR STOX GBL ESG SLT 33939L688 BBG00D9WQ9Z5 7,811,784 57,889 SH   SOLE   57,889 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 BBG00V9VQ4K4 87,581 33,685 SH   SOLE   33,685 0 0
GERON CORP COM 374163103 BBG001S6TSX4 61,726 29,116 SH   SOLE   29,116 0 0
INCYTE CORP COM 45337C102 BBG001S8Q6N2 204,390 3,538 SH   SOLE   3,538 0 0
INVESCO EXCH TRADED FD TR II SR LN ETF 46138G508 BBG001V0MBC0 2,484,669 118,372 SH   SOLE   118,372 0 0
INVESCO EXCH TRD SLF IDX FD INVSCO 30 CORP 46138J460 BBG00X3HYBX8 679,590 43,619 SH   SOLE   43,619 0 0
INVESCO EXCHANGE TRADED FD T DORSEY WRIGHT MO 46137V837 BBG001SJ09N0 1,492,205 19,382 SH   SOLE   19,382 0 0
ISHARES INC CUR HD MSCI EM 46434G509 BBG0076SN965 1,618,276 68,454 SH   SOLE   68,454 0 0
ISHARES TR 0-5 YR TIPS ETF 46429B747 BBG001TG5H89 2,079,017 21,451 SH   SOLE   21,451 0 0
ISHARES TR 20 YR TR BD ETF 464287432 BBG001S8MLN3 534,623 6,028 SH   SOLE   6,028 0 0
ISHARES TR 3 7 YR TREAS BD 464288661 BBG001SSD812 999,668 8,831 SH   SOLE   8,831 0 0
ISHARES TR 7-10 YR TRSY BD 464287440 BBG001S80936 1,095,317 11,957 SH   SOLE   11,957 0 0
ISHARES TR CORE HIGH DV ETF 46429B663 BBG001V0XLT8 6,072,746 61,409 SH   SOLE   61,409 0 0
ISHARES TR CORE S&P500 ETF 464287200 BBG001SFB7R6 2,412,860 5,620 SH   SOLE   5,620 0 0
ISHARES TR ESG AW MSCI EAFE 46435G516 BBG00D7BBRS7 23,844,842 344,925 SH   SOLE   344,925 0 0
ISHARES TR FLTG RATE NT ETF 46429B655 BBG001V1QYX1 1,055,978 20,750 SH   SOLE   20,750 0 0
ISHARES TR GLB INFRASTR ETF 464288372 BBG001SYVWT6 6,295,138 145,421 SH   SOLE   145,421 0 0
ISHARES TR GLOBAL REIT ETF 46434V647 BBG006S5D3J3 313,906 14,828 SH   SOLE   14,828 0 0
ISHARES TR IBOXX INV CP ETF 464287242 BBG001S60QR6 3,146,720 30,846 SH   SOLE   30,846 0 0
ISHARES TR JPMORGAN USD EMG 464288281 BBG001SQS9Y2 2,578,198 31,244 SH   SOLE   31,244 0 0
ISHARES TR MBS ETF 464288588 BBG001SSD8B1 2,008,922 22,623 SH   SOLE   22,623 0 0
ISHARES TR MSCI INDIA ETF 46429B598 BBG002DMN4B6 614,348 13,893 SH   SOLE   13,893 0 0
ISHARES TR MSCI USA MIN VOL 46429B697 BBG0025X2G81 837,148 11,567 SH   SOLE   11,567 0 0
ISHARES TR MSCI USA MMENTM 46432F396 BBG004FPV022 11,931,553 85,406 SH   SOLE   85,406 0 0
ISHARES TR SHORT TREAS BD 464288679 BBG001SSD803 1,342,612 12,154 SH   SOLE   12,154 0 0
ISHARES TR TIPS BD ETF 464287176 BBG001SD9RM5 1,896,735 18,288 SH   SOLE   18,288 0 0
JASPER THERAPEUTICS INC COM 471871103 BBG00QPZNPB4 77,556 110,792 SH   SOLE   110,792 0 0
JPMORGAN CHASE & CO COM 46625H100 BBG001S8CRC3 503,534 3,472 SH   SOLE   3,472 0 0
KRONOS BIO INC COM 50107A104 BBG00L072932 51,959 39,968 SH   SOLE   39,968 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 BBG00KFWZCX7 84,690 65,649 SH   SOLE   65,649 0 0
NKARTA INC COM 65487U108 BBG00JXHS9H6 55,124 39,657 SH   SOLE   39,657 0 0
NVIDIA CORPORATION COM 67066G104 BBG001S5TZJ6 755,759 1,737 SH   SOLE   1,737 0 0
ORCHARD THERAPEUTICS PLC SPON ADS NEW 68570P200 BBG00M62QW74 109,634 14,183 SH   SOLE   14,183 0 0
PFIZER INC COM 717081103 BBG001S5V466 252,731 7,617 SH   SOLE   7,617 0 0
PIMCO ETF TR 15+ YR US TIPS 72201R304 BBG001T5HFW7 8,631,234 164,248 SH   SOLE   164,248 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 BBG00BNTZ9J8 59,428 24,969 SH   SOLE   24,969 0 0
PROSHARES TR PSHS ULTRUSS2000 74347R842 BBG001S5RN32 438,356 14,501 SH   SOLE   14,501 0 0
REGENERON PHARMACEUTICALS COM 75886F107 BBG001S6PX49 241,130 293 SH   SOLE   293 0 0
SCHWAB STRATEGIC TR US SML CAP ETF 808524607 BBG001T5XQW5 428,544 10,346 SH   SOLE   10,346 0 0
SELECT SECTOR SPDR TR RL EST SEL SEC 81369Y860 BBG00B597137 946,013 27,766 SH   SOLE   27,766 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 BBG001S72SM3 9,249,656 21,638 SH   SOLE   21,638 0 0
SPDR SER TR BLOOMBERG HIGH Y 78468R622 BBG001SQS7X7 285,248 3,155 SH   SOLE   3,155 0 0
SPDR SER TR BLOOMBERG INVT 78468R200 BBG0029J2J00 1,883,352 61,307 SH   SOLE   61,307 0 0
SPDR SER TR FTSE INT GVT ETF 78464A490 BBG001STK554 4,932,116 126,756 SH   SOLE   126,756 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 BBG00Z0GRC64 47,539 17,672 SH   SOLE   17,672 0 0
TIDAL ETF TR RPAR RISK PARI 886364603 BBG00R24NZQ8 353,238 20,174 SH   SOLE   20,174 0 0
UNITEDHEALTH GROUP INC COM 91324P102 BBG001S6WCJ1 274,506 542 SH   SOLE   542 0 0
VANGUARD CHARLOTTE FDS TOTAL INT BD ETF 92203J407 BBG004N1LGK2 1,578,653 33,006 SH   SOLE   33,006 0 0
VANGUARD INDEX FDS REAL ESTATE ETF 922908553 BBG001SMD2X3 4,922,401 65,058 SH   SOLE   65,058 0 0
VANGUARD INDEX FDS SMALL CP ETF 922908751 BBG001SHTTV0 2,413,941 12,768 SH   SOLE   12,768 0 0
VANGUARD INDEX FDS VALUE ETF 922908744 BBG001SHVR78 1,574,168 11,412 SH   SOLE   11,412 0 0
VANGUARD INTL EQUITY INDEX F FTSE EMR MKT ETF 922042858 BBG001SHTTZ6 15,970,577 407,309 SH   SOLE   407,309 0 0
VANGUARD INTL EQUITY INDEX F GLB EX US ETF 922042676 BBG001TCVT65 3,454,878 88,745 SH   SOLE   88,745 0 0
VANGUARD TAX-MANAGED FDS VAN FTSE DEV MKT 921943858 BBG001SSPWL4 13,404,018 306,588 SH   SOLE   306,588 0 0
VANGUARD WHITEHALL FDS EM MK GOV BD ETF 921946885 BBG004N1LYJ5 361,973 6,119 SH   SOLE   6,119 0 0
VANGUARD WORLD FD EXTENDED DUR 921910709 BBG001SV5CV2 4,761,234 67,987 SH   SOLE   67,987 0 0
WISDOMTREE TR US SMALLCAP FUND 97717W562 BBG001SSZBC9 1,435,485 33,175 SH   SOLE   33,175 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101 BBG011FJXVZ5 95,462 14,464 SH   SOLE   14,464 0 0