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Condensed Consolidated Statements of Stockholders’ Equity - USD ($)
$ in Thousands
Total
Preferred Stock
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2018   0 31,825,769      
Beginning balance at Dec. 31, 2018 $ 136,949 $ 0 $ 32 $ 250,316 $ (18) $ (113,381)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (in shares)     23,345      
Vesting of restricted common stock 7     7    
Exercise of stock options (in shares)     181,521      
Exercise of stock options 257     257    
Stock-based compensation expense 1,953     1,953    
Unrealized gain on investments 16       16  
Net loss (20,299)         (20,299)
Ending balance (in shares) at Mar. 31, 2019   0 32,030,635      
Ending balance at Mar. 31, 2019 118,883 $ 0 $ 32 252,533 (2) (133,680)
Beginning balance (in shares) at Dec. 31, 2018   0 31,825,769      
Beginning balance at Dec. 31, 2018 136,949 $ 0 $ 32 250,316 (18) (113,381)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Unrealized gain on investments 18          
Net loss (62,873)          
Ending balance (in shares) at Sep. 30, 2019   0 32,072,030      
Ending balance at Sep. 30, 2019 80,546 $ 0 $ 32 256,768 0 (176,254)
Beginning balance (in shares) at Mar. 31, 2019   0 32,030,635      
Beginning balance at Mar. 31, 2019 118,883 $ 0 $ 32 252,533 (2) (133,680)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (in shares)     13,692      
Vesting of restricted common stock 7     7    
Exercise of stock options (in shares)     1,379      
Exercise of stock options 1     1    
Stock-based compensation expense 2,135     2,135    
Unrealized gain on investments 3       3  
Net loss (20,941)         (20,941)
Ending balance (in shares) at Jun. 30, 2019   0 32,045,706      
Ending balance at Jun. 30, 2019 100,088 $ 0 $ 32 254,676 1 (154,621)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (in shares)     13,691      
Vesting of restricted common stock 7     7    
Exercise of stock options (in shares)     12,633      
Exercise of stock options 23     23    
Stock-based compensation expense 2,062     2,062    
Unrealized gain on investments (1)       (1)  
Net loss (21,633)         (21,633)
Ending balance (in shares) at Sep. 30, 2019   0 32,072,030      
Ending balance at Sep. 30, 2019 80,546 $ 0 $ 32 256,768 0 (176,254)
Beginning balance (in shares) at Dec. 31, 2019   0 32,170,605      
Beginning balance at Dec. 31, 2019 60,197 $ 0 $ 32 259,018 0 (198,853)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (in shares)     13,390      
Vesting of restricted common stock 7     7    
Exercise of stock options (in shares)     137,213      
Exercise of stock options 226     226    
Stock-based compensation expense 1,955     1,955    
Net loss (23,041)         (23,041)
Ending balance (in shares) at Mar. 31, 2020   0 32,321,208      
Ending balance at Mar. 31, 2020 39,344 $ 0 $ 32 261,206 0 (221,894)
Beginning balance (in shares) at Dec. 31, 2019   0 32,170,605      
Beginning balance at Dec. 31, 2019 $ 60,197 $ 0 $ 32 259,018 0 (198,853)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Exercise of stock options (in shares) 159,998          
Unrealized gain on investments $ 0          
Net loss (64,616)          
Ending balance (in shares) at Sep. 30, 2020   0 46,184,087      
Ending balance at Sep. 30, 2020 50,430 $ 0 $ 46 313,853 0 (263,469)
Beginning balance (in shares) at Mar. 31, 2020   0 32,321,208      
Beginning balance at Mar. 31, 2020 39,344 $ 0 $ 32 261,206 0 (221,894)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of common stock in public offering, net of fees (in shares)     13,800,000      
Issuance of common stock in public offering, net of fees 48,407   $ 14 48,393    
Vesting of restricted common stock (in shares)     11,491      
Vesting of restricted common stock 5     5    
Exercise of stock options (in shares)     3,944      
Exercise of stock options 9     9    
Stock-based compensation expense 2,093     2,093    
Net loss (20,652)         (20,652)
Ending balance (in shares) at Jun. 30, 2020   0 46,136,643      
Ending balance at Jun. 30, 2020 69,206 $ 0 $ 46 311,706 0 (242,546)
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of stock under the Employee Stock Purchase Plan (in shares)     28,603      
Issuance of stock under the Employee Stock Purchase Plan 92     92    
Exercise of stock options (in shares)     18,841      
Exercise of stock options 11     11    
Stock-based compensation expense 2,045     2,045    
Fees associated with public offering of common stock (1)     (1)    
Unrealized gain on investments 0          
Net loss (20,923)         (20,923)
Ending balance (in shares) at Sep. 30, 2020   0 46,184,087      
Ending balance at Sep. 30, 2020 $ 50,430 $ 0 $ 46 $ 313,853 $ 0 $ (263,469)