X0306 4 2017-09-05 0 0001533040 RXi Pharmaceuticals Corp RXII 0001694380 Eliseev Alexey C/O 257 SIMARANO DRIVE, SUITE 101 MARLBOROUGH MA 01752 0 1 0 0 Chief Business Officer Common stock, par value $0.0001 2017-09-05 4 S 0 26181 0.5571 D 1100931 D Common stock, par value $0.0001 2017-09-06 4 S 0 91907 0.5365 D 1009024 D Common stock, par value $0.0001 2017-09-07 4 S 0 58712 0.5283 D 950312 D The sales reported were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Represents the weighted average sale price. The lowest price at which shares were sold was $0.55 and the highest price at which shares were sold was $0.58.The reporting person hereby undertakes to provide upon request to the SEC staff or other appropriate persons full information regarding the number of shares and prices at which the transaction was effected. Represents the weighted average sale price. The lowest price at which shares were sold was $0.525 and the highest price at which shares were sold was $0.561.The reporting person hereby undertakes to provide upon request to the SEC staff or other appropriate persons full information regarding the number of shares and prices at which the transaction was effected. Represents the weighted average sale price. The lowest price at which shares were sold was $0.52 and the highest price at which shares were sold was $0.545.The reporting person hereby undertakes to provide upon request to the SEC staff or other appropriate persons full information regarding the number of shares and prices at which the transaction was effected. Caitlin Kontulis, attorney-in-fact 2017-09-07