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Income Taxes - Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 21.00%
State taxes, net of federal benefit 5.90% 5.90%
Federal and state research and development tax credits 3.70% 4.70%
Other 0.10% 0.30%
Nondeductible items (1.00%) (1.30%)
Change in valuation allowance (29.70%) (30.60%)
Effective income tax rate 0.00% 0.00%