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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Operating activities    
Net loss $ (28,039) $ (23,347)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 176 182
Stock-based compensation expense 1,857 1,691
Amortization of premiums and discounts on marketable securities (685) (2,116)
Reduction in the carrying value of right-of-use assets 152 134
Non-cash interest expense and amortization of debt issuance costs 325 263
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,272) (510)
Accounts payable 1,140 1,000
Accrued expenses (3,211) (3,304)
Operating lease liabilities (244) (220)
Prepaid expenses, net of current portion 652 1,694
Net cash used in operating activities (29,149) (24,533)
Investing activities    
Purchases of marketable securities (17,934) (49,324)
Sales and maturities of marketable securities 51,618 59,750
Purchases of property and equipment 0 (32)
Net cash provided by (used in) investing activities 33,684 10,394
Financing activities    
Proceeds from Issuance of Common Stock 228 0
Proceeds from exercise of stock options 0 11
Proceeds from issuance of common stock for cash under Employee Stock Purchase Plan 0 148
Net cash provided by financing activities 228 159
Net increase (decrease) in cash, cash equivalents, and restricted cash 4,763 (13,980)
Effect of foreign currency exchange rate in cash 2 10
Cash, cash equivalents and restricted cash at beginning of period 21,392 34,899
Cash, cash equivalents and restricted cash at end of period 26,157 20,929
Supplemental cash flow information:    
Cash and cash equivalents 25,846 20,618
Restricted cash 311 311
Cash, cash equivalents and restricted cash at end of period $ 26,157 $ 20,929