X0306 4 2022-04-19 0 0001693011 Inozyme Pharma, Inc. INZY 0001713663 Longitude Capital Partners III, LLC 2740 SAND HILL ROAD SECOND FLOOR MENLO PARK CA 94025 0 0 1 0 0001674099 Longitude Venture Partners III, L.P. 2740 SAND HILL RD 2ND FLOOR MENLO PARK CA 94025 0 0 1 0 0001431159 Tammenoms Bakker Juliet 2740 SAND HILL ROAD, 2ND FLOOR MENLO PARK CA 94025 0 0 1 0 0001253886 ENRIGHT PATRICK G 2740 SAND HILL RD 2ND FLOOR MENLO PARK CA 94025 0 0 1 0 Common Stock 2022-04-19 4 P 0 1355000 3.69 A 4174379 I By Longitude Venture Partners III, L.P. These shares are held by Longitude Venture Partners III, L.P. ("LVP III"). Longitude Capital Partners III, LLC ("LCP III") is the general partner of LVP III and may be deemed to have voting and dispositive power over the shares held by LVP III. Patrick G. Enright and Juliet Tammenoms Bakker are managing members of LCP III and may be deemed to share voting and dispositive power with respect to the shares held by LVP III. Each of LCP III, Mr. Enright and Ms. Tammenoms Bakker disclaims beneficial ownership of such shares and this report shall not be deemed an admission that any of them is the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their respective pecuniary interests therein. /s/ Patrick G. Enright 2022-04-21 /s/ Juliet Tammenoms Bakker 2022-04-21 Longitude Venture Partners III, L.P.; By /s/ Patrick G. Enright, Managing Member of the general partner 2022-04-21 Longitude Capital Partners III, LLC; By /s/ Patrick G. Enright, Managing Member 2022-04-21