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Stock-based Compensation - Stock Options Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Number of Options    
Outstanding (in shares) 9,760,657  
Granted (in shares) 241,000  
Exercised (in shares) (37,331)  
Cancelled (in shares) (455,318)  
Outstanding (in shares) 9,509,008 9,760,657
Exercisable (in shares) 3,744,057  
Unvested (in shares) 5,764,951  
Weighted- Average Exercise Price    
Outstanding (usd per share) $ 39.43  
Granted (usd per share) 18.17  
Exercised (usd per share) 5.29  
Cancelled (usd per share) 39.14  
Outstanding (usd per share) 38.89 $ 39.43
Exercisable, weighted-average exercise price (usd per share) 28.97  
Unvested, weighted-average exercise price (usd per share) $ 45.57  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract]    
Outstanding, weighted-average remaining contractual, term 7 years 9 months 8 years 2 months 1 day
Exercisable, weighted-average remaining contractual, term 6 years 3 months 21 days  
Unvested, weighted-average remaining contractual, term 8 years 7 months 24 days  
Outstanding, aggregate intrinsic value, outstanding $ 8,280 $ 8,050
Exercisable, aggregate intrinsic value 8,250  
Unvested, aggregate intrinsic value $ 20  
Assumed from acquisition (in shares) 72,410