Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating expenses:
Research and development	$ 7,995	$ 16,547
General and administrative	6,132	7,287
Restructuring and other charges	18,003	0
Total operating expenses	32,130	23,834
Loss from operations	(32,130)	(23,834)
Interest and other income, net	2,960	884
Net loss	$ (29,170)	$ (22,950)
Net loss per share, basic	$ (0.48)	$ (0.39)
Net loss per share, diluted	$ (0.48)	$ (0.39)
Weighted average common shares outstanding, basic	60,645,652	58,799,157
Weighted average common shares outstanding, diluted	60,645,652	58,799,157
Comprehensive loss:
Net loss	$ (29,170)	$ (22,950)
Other comprehensive gain (loss):
Unrealized gains (losses) on marketable securities	165	(439)
Total other comprehensive gain (loss)	165	(439)
Total comprehensive loss	$ (29,005)	$ (23,389)