Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020	$ 143,906	$ 49	$ 398,311	$ (23)	$ (254,431)
Beginning balance, shares at Dec. 31, 2020		48,533,135
Issuance of common stock upon private investment, net of offering costs	86,097	$ 10	86,087
Issuance of common stock upon private investment, net of offering costs, shares		9,599,998
Vesting of restricted stock, shares		218,464
Issuance of common stock upon exercise of stock options	3,294		3,294
Issuance of common stock upon exercise of stock options, shares		411,685
Issuance of common stock under Employee Stock Purchase Plan	86		86
Issuance of common stock under Employee Stock Purchase Plan, shares		13,989
Stock-based compensation expense	8,125		8,125
Unrealized gains (losses) on marketable securities	24			24
Net loss	(51,844)				(51,844)
Ending balance at Sep. 30, 2021	189,688	$ 59	495,903	1	(306,275)
Ending balance, shares at Sep. 30, 2021		58,777,271
Beginning balance at Dec. 31, 2020	143,906	$ 49	398,311	(23)	(254,431)
Beginning balance, shares at Dec. 31, 2020		48,533,135
Net loss	(71,100)
Ending balance at Dec. 31, 2021	172,672	$ 59	498,210	(30)	(325,567)
Ending balance, shares at Dec. 31, 2021		58,799,157
Beginning balance at Jun. 30, 2021	202,892	$ 59	491,679	2	(288,848)
Beginning balance, shares at Jun. 30, 2021		58,508,735
Vesting of restricted stock, shares		209,998
Issuance of common stock upon exercise of stock options	425		425
Issuance of common stock upon exercise of stock options, shares		58,538
Stock-based compensation expense	3,799		3,799
Unrealized gains (losses) on marketable securities	(1)			(1)
Net loss	(17,427)				(17,427)
Ending balance at Sep. 30, 2021	189,688	$ 59	495,903	1	(306,275)
Ending balance, shares at Sep. 30, 2021		58,777,271
Beginning balance at Dec. 31, 2021	172,672	$ 59	498,210	(30)	(325,567)
Beginning balance, shares at Dec. 31, 2021		58,799,157
Issuance of common stock	2,763	$ 2	2,761
Issuance of common stock, shares		1,644,200
Vesting of restricted stock, shares		62,459
Issuance of common stock under Employee Stock Purchase Plan	49		49
Issuance of common stock under Employee Stock Purchase Plan, shares		49,704
Stock-based compensation expense	5,257		5,257
Unrealized gains (losses) on marketable securities	(432)			(432)
Net loss	(56,284)				(56,284)
Ending balance at Sep. 30, 2022	124,025	$ 61	506,277	(462)	(381,851)
Ending balance, shares at Sep. 30, 2022		60,555,520
Beginning balance at Jun. 30, 2022	135,678	$ 59	502,009	(602)	(365,788)
Beginning balance, shares at Jun. 30, 2022		58,848,861
Issuance of common stock	2,763	$ 2	2,761
Issuance of common stock, shares		1,644,200
Vesting of restricted stock, shares		62,459
Stock-based compensation expense	1,507		1,507
Unrealized gains (losses) on marketable securities	140			140
Net loss	(16,063)				(16,063)
Ending balance at Sep. 30, 2022	$ 124,025	$ 61	$ 506,277	$ (462)	$ (381,851)
Ending balance, shares at Sep. 30, 2022		60,555,520