Collaboration, License and Other Agreements - BMS Agreement and Amendment (Details)		1 Months Ended				3 Months Ended			6 Months Ended		12 Months Ended	54 Months Ended
	Feb. 27, 2020 USD ($)	Nov. 30, 2020 USD ($)	Aug. 31, 2020 USD ($)	Mar. 31, 2018 USD ($)	Jul. 31, 2016 USD ($) product	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2021 USD ($)
License and other agreements
Research and development						$ 218,480,000	$ 77,428,000		$ 337,579,000	$ 184,539,000
BMS Agreement
License and other agreements
Upfront payment under the BMS Amendment			$ 5,000,000	$ 50,000,000
Maximum obligated payment for each licensed product to achieve commercial milestone			$ 22,500,000
BMS Agreement | Collaborative arrangement
License and other agreements
Development milestone payment to be paid												$ 12,000,000
Payment required due to achievement of milestone	$ 40,000,000
Required milestone payments capitalized to intangible asset	$ 40,000,000
Milestone payments								$ 5,000,000			$ 40,000,000
Accrued expense for payment due following regulatory approval								$ 5,000,000					$ 5,000,000
Research and development						0	0		0	0
Royalty expense						$ 19,354,000	$ 9,293,000		$ 31,709,000	$ 13,678,000
BMS Agreement | Collaborative arrangement | Maximum
License and other agreements
Milestone payment to be paid upon regulatory achievement					$ 127,500,000
Milestone payment to be paid for any product other than rimegepant					74,500,000
Commercial milestone payment to be paid					$ 150,000,000
BMS Agreement | Collaborative arrangement | Minimum
License and other agreements
Number of licensed products | product					1
November 2020 BMS Amendment | Collaborative arrangement
License and other agreements
Commercial milestone payment to be paid		$ 150,000,000
Net sales threshold for milestone (percent)		10.00%
Development milestone payment to be paid		$ 17,500,000