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Acquisitions (Details) - USD ($)
3 Months Ended 6 Months Ended
Apr. 04, 2022
Jan. 04, 2021
Jun. 30, 2022
Dec. 31, 2021
Jun. 30, 2021
Mar. 31, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2020
Amounts recorded:                  
Research and development     $ 218,480,000   $ 77,428,000   $ 337,579,000 $ 184,539,000  
Channel                  
Amounts recorded:                  
Upfront cash payment $ 35,000,000                
Stock issued in acquisition, number of shares 493,254                
Stock issued in acquisition $ 58,747,000                
Potential developmental and regulatory milestones on BHV-7000 325,000,000                
Potential developmental and regulatory milestones on Kv7 pipeline development 250,000,000                
Potential commercial sales based milestones of BHV-7000 $ 562,500,000                
Research and development     93,747,000            
Recorded liability     $ 25,000,000       $ 25,000,000    
Kleo                  
Business Acquisition [Line Items]                  
Fair value of consideration transferred   $ 20,043,000              
Issuance of shares   115,836              
Amount received per contingent value right upon regulatory approval   $ 1              
Contingent value right term period   30 months              
Maximum amount payable for contingent value rights   $ 17,300,000              
Recognized gain on contingent value right       $ 1,457,000          
Post-transaction ownership percentage   100.00%              
Fair value of existing interest   $ 6,437,000              
Gain resulting from remeasurement of fair value of existing interest           $ 5,261,000      
Amounts recorded:                  
Net working capital   573,000              
Property, plant and equipment, net   1,257,000              
Intangible assets, in progress research and development   18,400,000              
Debt assumed   1,577,000              
Goodwill   $ 1,390,000              
Kleo                  
Business Acquisition [Line Items]                  
Ownership percentage                 41.90%
Equity method investment                 $ 1,176,000