Liability Related to Sale of Future Royalties, net - Reduction to Research and Development Expenses (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2022	Mar. 31, 2021
2020 RPI Funding Agreement
Liability For Sale of Future Royalties [Line Items]
Reduction in research and development expenses	$ 6,943	$ 190

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

No definition available.

Name:	us-gaap_DebtInstrumentLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration