Balance Sheet Components - Prepaid Expenses (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Prepaid Expenses
Prepaid clinical trial costs	$ 58,562	$ 42,578
Prepaid manufacturing	8,856	17,448
Prepaid commercial costs	33,248	15,732
Other prepaid expenses	4,225	13,080
Prepaid expenses	$ 104,891	$ 88,838

Amount of asset related to consideration paid in advance for costs that provide economic benefits within a future period of one year or the normal operating cycle, if longer.

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Name:	us-gaap_PrepaidExpenseCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant