License and Other Agreements - Revenue Participation Rights (Details) - USD ($)	1 Months Ended	3 Months Ended
	Jun. 30, 2018	Mar. 31, 2021	Mar. 31, 2020	Aug. 31, 2020
License and other agreements
Interest expense on liability related to sale of future royalties		$ 13,508,000	$ 8,425,000
2018 RPI Funding Agreement
License and other agreements
Proceeds from royalty agreement	$ 100,000,000
Interest expense on liability related to sale of future royalties		11,419,000
Payments under funding agreement		736,000	0
2020 RPI Funding Agreement
License and other agreements
Interest expense on liability related to sale of future royalties		$ 2,089,000
Payments under funding agreement			$ 140,000
Sales-based participation rights sold, value				$ 250,000,000
Revenue Participation Right, tranche one | 2018 RPI Funding Agreement
License and other agreements
Participation rate for revenue participation right (percent)	2.10%
Revenue Participation Right, tranche one | 2018 RPI Funding Agreement | Maximum
License and other agreements
Annual global net sales threshold for revenue participation right	$ 1,500,000,000
Revenue Participation Right, tranche two | 2018 RPI Funding Agreement
License and other agreements
Participation rate for revenue participation right (percent)	1.50%