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Warrants - Narrative (Details) - USD ($)
1 Months Ended 3 Months Ended
Jan. 26, 2018
Aug. 31, 2017
Aug. 30, 2016
May 31, 2019
Mar. 31, 2019
Mar. 31, 2020
Warrants            
Reclassification of fair value of warrant liability to shareholders' equity $ 5,203,000          
Proceeds from exercise of warrants         $ 1,998,000  
Value of common stock issued           $ 282,833,000
FCCDC Warrants            
Warrants            
Number of securities called by warrants (shares)       100,000    
Exercise price of warrants (in dollars per share)       $ 56.46    
Guarantor and Co-Guarantor Warrants            
Warrants            
Number of securities called by warrants (shares)         107,500  
Exercise price of warrants (in dollars per share)         $ 9,291.1000  
FCCDC Agreement | Collaborative arrangement            
Warrants            
Common stock issued (shares)       100,000    
Value of common stock issued       $ 5,646,000    
Development milestone payment to be paid       4,500,000    
Development milestone payments to be paid per each additional NDA filing       $ 1,000,000    
Credit Agreement | Wells Fargo Term Loan            
Warrants            
Credit agreement term     1 year      
Principal amount     $ 5,000,000      
Proceeds from borrowings     $ 5,000,000      
Principal repayment   $ 5,000,000