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Fair Value of Financial Assets and Liabilities
9 Months Ended
Sep. 30, 2019
Fair Value Disclosures [Abstract]  
Fair Value of Financial Assets and Liabilities Fair Value of Financial Assets and Liabilities
The Company held no financial assets measured at fair value on a recurring basis as of September 30, 2019, and no financial assets or liabilities measured at fair value on a recurring basis as of December 31, 2018.
The following tables present information about the Company's financial liability measured at fair value on a recurring basis and indicate the level of the fair value hierarchy utilized to determine such fair value:
Fair Value Measurement as of September 30, 2019 Using:
Level 1Level 2Level 3Total
Liabilities:
Derivative liability$—  $—  $36,795  $36,795  
$—  $—  $36,795  $36,795  

The following table provides a roll forward from transaction date of the Series A preferred shares (see Note 8) to September 30, 2019 of the aggregate fair value of the Company’s derivative liability for which fair value is determined by Level 3 inputs:
Derivative
Liability
Transaction date balance$33,815  
Change in fair value2,980  
Balance at September 30, 2019$36,795  

Valuation of Derivative Liability
The fair value of the derivative liability recognized in connection with the Series A preferred shares agreement with RPI Finance Trust ("RPI"), as described in Note 8, was determined based on significant inputs not observable in the market, which represents a Level 3 measurement within the fair value hierarchy. The fair value of the derivative liability relates to certain scenarios outlined in the agreement that would result in accelerated payments as compared to the agreement's host instrument. The with-and-without valuation method was used to determine the fair value of the embedded derivatives within the agreement. As inputs into the valuation, the Company considered the type and probability of occurrence of certain events, the amount of the payments, the expected timing of certain events, and a risk-adjusted discount rate. In accordance with ASC 815, Derivatives and Hedging, the fair value of the derivative was recorded on the balance sheet as a derivative liability with changes in fair
value recorded in other income (expense) in the condensed consolidated statements of operations and comprehensive loss. If factors change and different assumptions are used, the fair value of the derivative liability and related gains or losses could be materially different in the future.
Valuation of Liability Related to Sale of Future Royalties
In June 2018, and as described in Note 7, the Company entered into a funding agreement with RPI, accounted for as a liability financing. As of September 30, 2019, the fair value of the liability related to sale of future royalties, used in determining the effective interest rate of the liability, is based on the Company's current estimates of future royalties expected to be paid to RPI over the life of the arrangement, which is considered Level 3.