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License and Other Agreements (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
May 31, 2019
Mar. 31, 2019
Mar. 31, 2018
Jan. 31, 2018
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2019
Jun. 30, 2019
Jun. 30, 2018
Mar. 31, 2018
License and other agreements                    
Value of common stock issued             $ 21,221 $ 281,100 $ 43,842 $ 52,013
FCCDC Warrants                    
License and other agreements                    
Number of securities called by warrants (shares) 100,000                  
Exercise price of warrants (in dollars per share) $ 56.46                  
Catalent Agreement | Collaborative arrangement                    
License and other agreements                    
Last patent right expiration period (in years)       10 years            
Automatic extension period (in years)       1 year            
Catalent Agreement | Collaborative arrangement | Maximum                    
License and other agreements                    
Milestone payment to be paid upon regulatory achievement       $ 1,500            
BMS Agreement                    
License and other agreements                    
Upfront payment under the BMS Amendment     $ 50,000              
Biotech Value Advisors Agreement | Collaborative arrangement | Maximum                    
License and other agreements                    
Commercial milestone payment to be paid   $ 2,000                
FCCDC Agreement | Collaborative arrangement                    
License and other agreements                    
Common stock issued (shares) 100,000                  
Value of common stock issued $ 5,646                  
Development milestone payment to be paid 4,500                  
Development milestone payments to be paid per each additional NDA filing 1,000                  
Performance milestone payment to be paid $ 1,500                  
Time period for payment of performance milestone 30 months                  
FCCDC Agreement | Collaborative arrangement | Minimum                    
License and other agreements                    
Earned royalty payment per agreement (percent) 0.00%                  
FCCDC Agreement | Collaborative arrangement | Maximum                    
License and other agreements                    
Earned royalty payment per agreement (percent) 10.00%                  
Yale Agreement | Collaborative arrangement                    
License and other agreements                    
Milestone payment to be paid upon regulatory achievement $ 2,000                  
Common stock issued (shares)           250,000        
Right to purchase securities in specified future equity offering (as a percent)           10.00%        
Minimum annual royalty payment to be paid upon sale of product $ 1,000                  
Notice period to terminate agreement 90 days                  
Yale Agreement | Collaborative arrangement | Maximum                    
License and other agreements                    
Extension of due diligence requirements (in years) 1 year                  
Amount of payment subject to due diligence extension $ 150                  
MGH Agreement | Collaborative arrangement | Minimum                    
License and other agreements                    
Royalties to be paid per agreement (percent)         0.00%          
MGH Agreement | Collaborative arrangement | Maximum                    
License and other agreements                    
Upfront payment under the BMS Amendment         $ 750          
Commercial milestone payment to be paid         $ 2,500          
Royalties to be paid per agreement (percent)         10.00%