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Net Loss Per Share - Antidilutive Securities Excluded from Computation of Net Loss per Share (Details) - shares
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Securities excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from calculation of diluted net loss per share 8,667,265 6,203,885
Options to purchase common shares    
Securities excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from calculation of diluted net loss per share 8,560,514 5,982,134
Warrants to purchase common shares    
Securities excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from calculation of diluted net loss per share 106,751 221,751