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Commitments and Contingencies - Narrative (Details) - USD ($)
$ in Thousands
Jun. 30, 2019
Dec. 31, 2018
Jan. 01, 2018
Other Commitments [Line Items]      
Accrued clinical trial costs $ 8,145 $ 6,753  
New Headquarters, New Haven, CT      
Other Commitments [Line Items]      
Lease agreement, term (in months)     85 months
Renewal term (in months)     120 months
Value of property with option to purchase     $ 2,700
BMS Agreement | Required payment on commencement of Phase 1 clinical trial      
Other Commitments [Line Items]      
Accrued clinical trial costs 2,000 2,000  
BMS Agreement | Required payment on commencement of Phase 2 clinical trial      
Other Commitments [Line Items]      
Accrued clinical trial costs 4,000 $ 4,000  
BMS Agreement | Required payment related to Rimegepant NDA filing      
Other Commitments [Line Items]      
Accrued clinical trial costs $ 7,500