215 Church Street New Haven, CT 06510 VIA EDGAR

December 10, 2018

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

Attn: Jeffrey Gabor

Re: Biohaven Pharmaceutical Holding Company Ltd.

Registration Statement on Form S-1

File No. 333-228736

Acceleration Request

Requested Date: Wednesday, December 12, 2018

Requested Time: 4:30 P.M. Eastern Standard Time

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant (the “Registrant”) hereby requests that the Securities and Exchange Commission (the “Commission”) take appropriate action to cause the above-referenced Registration Statement on Form S-1 (File No. 333-228736) to become effective on December 12, 2018 at 4:30 p.m., Eastern Standard Time, or as soon thereafter as is practicable, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff (the “Staff”).

Once the Registration Statement has been declared effective, please orally confirm that event with Madison Jones of Cooley LLP, counsel to the Registrant, at (202) 728-7087 or William DuVal of Cooley LLP at (703) 456-8663.

Very truly yours,
Biohaven Pharmaceutical Holding Company Ltd.
By:	/s/ James Engelhart
	James Engelhart
	Chief Financial Officer

cc: Darren K. DeStefano, Cooley LLP

Brian F. Leaf, Cooley LLP