X0306 4 2019-02-04 0 0001689813 Biohaven Pharmaceutical Holding Co Ltd. BHVN 0001262325 AGUIAR ERIC C/O AISLING CAPITAL LLC 888 SEVENTH AVENUE, 12TH FLOOR NEW YORK NY 10106 1 0 0 0 Common Shares 2019-02-04 4 M 0 10000 25.51 A 10000 I By Spouse Common Shares 2019-02-04 4 M 0 7609 20.79 A 17609 I By Spouse Common Shares 2019-02-04 4 M 0 17609 42.54 D 0 I By Spouse Employee Stock Option (Right to Buy) 25.51 2019-02-04 4 M 0 10000 0.00 D 2027-08-03 Common Shares 10000 30000 I By Spouse Employee Stock Option (Right to Buy) 20.79 2019-02-04 4 M 0 7609 0.00 D 2027-12-06 Common Shares 7609 22827 I By Spouse These exercises and sales were made pursuant to a 10b5-1 trading plan adopted by the Reporting Person's spouse. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $42.54 - $42.56, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. The shares underlying this option vest in four equal installments on July 5, 2018, 2019, 2020 and 2021, subject to the optionholder's continuous service with the Issuer at each vesting date. This employee stock option is held by the Reporting Person's spouse. The shares underlying this option vest in four equal installments on December 7, 2018, 2019, 2020 and 2021, subject to the optionholder's continuous service with the Issuer at each vesting date. /s/ Darren K. DeStefano, Attorney-in-fact 2019-02-06