X0306 4 2017-09-05 0 0001689813 Biohaven Pharmaceutical Holding Co Ltd. BHVN 0001262325 AGUIAR ERIC C/O AISLING CAPITAL LLC 888 SEVENTH AVENUE, 12TH FLOOR NEW YORK NY 10106 1 0 0 0 Employee Stock Option (right to buy) 37.54 2017-09-05 4 A 0 5000 0.00 A 2027-09-04 Common Shares 5000 5000 I By Spouse The shares underlying this option vest in four equal installments on September 5, 2018, 2019, 2020 and 2021, subject to the optionholder's continuous service with the issuer at each vesting date. This employee stock option is held by the reporting person's spouse. /s/ Darren K. DeStefano, Attorney-in-fact 2017-09-12