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License Agreements - Rutger Agreement (Details)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jun. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
License agreements          
Research and development   $ 34,996 $ 27,045 $ 66,755 $ 35,137
Rutgers Agreement | Collaborative arrangement          
License agreements          
License Costs $ 75        
Number of years the Company is required to pay Rutgers annual license maintenance fees 5 years        
Annual license maintenance fees after execution of the agreement $ 25        
Change of control fee 0.3        
Consideration payable upon change-of-control event $ 100        
Fair value of derivative liability $ 0 0   0  
Last patent right expiration period 10 years        
Research and development   $ 0 $ 0 $ 0 $ 72
Rutgers Agreement | Collaborative arrangement | Maximum          
License agreements          
Milestone payment to be paid $ 825        
Extension of due diligence requirements 1 year        
Amount of payment subject to due diligence extension $ 500        
Rutgers Agreement | Collaborative arrangement | Minimum          
License agreements          
Guaranteed royalties $ 100