Fair Value of Financial Assets and Liabilities (Details) $ in Thousands	3 Months Ended	12 Months Ended
Mar. 31, 2017 USD ($) director	Dec. 31, 2016 USD ($)
Fair value of Financial Assets and Liabilities
Transfer between levels 1 to level 2	$ 0	$ 0
Transfer between levels 2 to level 1	0	0
Transfer in and out of level 3	$ 0	$ 0
Number of directors to whom the Company agreed to issue warrants \| director	2
Expected dividend yield	0.00%
Probability of occurrence of event that was most probable of triggering the issuance of shares	85.00%	75.00%
Value of the contingently issuable equity	$ 18,750	$ 18,750
Discount assessed	0.00%	0.00%
Fair value of the contingent equity liability	$ 15,938	$ 14,063
Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	23,770	20,230
Level 3 \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	23,770	20,230
Warrants to purchase common shares \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	1,234	780
Warrants to purchase common shares \| Level 3 \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	1,234	780
Derivative liability \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	223	512
Derivative liability \| Level 3 \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	223	512
Contingent equity liability \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	22,313	18,938
Contingent equity liability \| Level 3 \| Recurring
Fair value of Financial Assets and Liabilities
Fair value of liabilities	$ 22,313	$ 18,938
Maximum
Fair value of Financial Assets and Liabilities
Expected timing of event that was most probable of triggering the issuance of shares	1 year	1 year

Carrying value of contingent consideration classified as long-term liability.

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Fair value of contingent consideration from license agreement that is classified in long-term liability.

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Represents the expected timing of event that was most probable of triggering the issuance of shares.

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Number of directors to whom the Company agreed to issue warrants to purchase common shares.

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Fair value, after the effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities not subject to a master netting arrangement and not elected to be offset.

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-Publisher FASB
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Expected dividends to be paid to holders of the underlying shares or financial instruments (expressed as a percentage of the share or instrument's price).

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Interest rate used to find the present value of an amount to be paid or received in the future as an input to measure fair value. For example, but not limited to, weighted average cost of capital (WACC), cost of capital, cost of equity and cost of debt.

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Percentage of likelihood a loan will not be repaid and instead default, used as an input to measure fair value.

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Amount of transfers of liabilities measured on a recurring basis out of Level 1 of the fair value hierarchy into Level 2.

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Amount of transfers of liabilities measured on a recurring basis out of Level 2 of the fair value hierarchy into Level 1.

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Amount of transfers of financial instrument classified as a liability into (out of) level 3 of the fair value hierarchy.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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