X0508 4 2025-03-20 0001534969 SERA PROGNOSTICS, INC. SERA 0001689757 Elliott Jeffrey Thomas C/O SERA PROGNOSTICS, INC. 2749 EAST PARLEYS WAY, SUITE 200 SALT LAKE CITY UT 84109 true false false false false Class A Common Stock 2025-03-20 4 A false 30534 0 A 30534 D Stock Option (right to buy) 3.93 2025-03-20 4 A false 47363 0 A 2035-03-20 Class A Common Stock 47363 47363 D Each share is represented by a restricted stock unit ("RSU"). These RSUs vest over three years as follows: 1/36 of the original grant amount vests in monthly installments for three years following the vesting commencement date, which is March 20, 2025, subject to the Reporting Person continuing to provide services to the issuer. These stock options vest over three years as follows: 1/36 of the original grant amount vests in monthly installments for three years following the vesting commencement date, which is March 20, 2025, subject to the Reporting Person continuing to provide services to the issuer. /s/ Benjamin G. Jackson, Attorney-in-fact 2025-03-21