X0306 4 2017-09-30 0001680378 SenesTech, Inc. SNES 0001689556 Dyer Cheryl Ann C/O SENESTECH, INC. 3140 N. CADEN COURT, SUITE 1 FLAGSTAFF AZ 86004 1 1 Pres. & Chief Research Officer Common Stock 2017-09-30 4 M 0 18333.0000 0.0000 A 450545.0000 D Common Stock 2017-09-30 4 F 0 5344.0000 1.8500 D 445201.0000 D Common Stock 2017-10-03 4 S 0 6000.0000 1.9680 D 439201.0000 D Common Stock 100000.0000 I 2016 Dyer Mayer Family Delaware Trust Restricted Stock Units 0.0000 2017-09-30 4 M 0 18333.0000 0.0000 D 2017-06-30 2019-06-30 Common Stock 18333.0000 128334.0000 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person July 5, 2017. The price shown is a weighted average sales price. The shares were sold at prices ranging from $1.92 to $2.10 per share. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The restricted stock units are settled for shares of common stock on a one-for-one basis. Date at which first vesting occurs is indicated. One-third of the total restricted stock units ("RSUs") granted vests on the first vesting date with the remaining RSUs to vest in equal quarterly tranches over the next 24 months of continuous service. Exhibit 24 power of attorney filed herewith. /s/ William Baker as Attorney-in-Fact 2017-10-03