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Segment Information - Operating Segment Information (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Segment Reporting Information [Line Items]    
Collaboration revenue $ 875 $ 20,558
Total research and development expenses 33,054 32,074
General and administrative expenses 10,124 10,274
Interest and other income 2,624 4,441
Provision for (benefit from) income taxes 38 0
Net (loss) income (39,717) (17,349)
Reportable Segment    
Segment Reporting Information [Line Items]    
Collaboration revenue 875 20,558
Total research and development expenses 33,054 32,074
General and administrative expenses 10,124 10,274
Interest and other income 2,624 4,441
Provision for (benefit from) income taxes 38 0
Net (loss) income (39,717) (17,349)
Reportable Segment | ENTR-601-44    
Segment Reporting Information [Line Items]    
Total research and development expenses 4,755 4,734
Reportable Segment | ENTR-601-45    
Segment Reporting Information [Line Items]    
Total research and development expenses 3,602 2,859
Reportable Segment | ENTR-601-50    
Segment Reporting Information [Line Items]    
Total research and development expenses 1,369 692
Reportable Segment | ENTR-601-51    
Segment Reporting Information [Line Items]    
Total research and development expenses 2,337 826
Reportable Segment | DMD franchise-wide    
Segment Reporting Information [Line Items]    
Total research and development expenses 1,739 0
Reportable Segment | Collaboration services    
Segment Reporting Information [Line Items]    
Total research and development expenses 234 876
Reportable Segment | Ocular programs    
Segment Reporting Information [Line Items]    
Total research and development expenses 461 270
Reportable Segment | Other preclinical and discovery    
Segment Reporting Information [Line Items]    
Total research and development expenses 599 987
Reportable Segment | Personnel related (including stock-based compensation)    
Segment Reporting Information [Line Items]    
Total research and development expenses 12,041 12,756
Reportable Segment | Facility related and other    
Segment Reporting Information [Line Items]    
Total research and development expenses $ 5,917 $ 8,074