Segment Information - Operating Segment Information (Details) - USD ($) $ in Thousands	3 Months Ended						9 Months Ended
	Sep. 30, 2025	Jun. 30, 2025	Mar. 31, 2025	Sep. 30, 2024	Jun. 30, 2024	Mar. 31, 2024	Sep. 30, 2025	Sep. 30, 2024
Segment Reporting Information [Line Items]
Collaboration revenue	$ 1,614			$ 19,570			$ 24,122	$ 173,384
Total research and development expenses	38,361			31,257			108,312	91,900
General and administrative expenses	10,304			9,971			31,500	28,606
Interest and other income	3,571			5,766			11,936	14,346
Provision for (benefit from) income taxes	654			(1,860)			832	2,729
Net (loss) income	(44,134)	$ (43,103)	$ (17,349)	(14,032)	$ 55,031	$ 23,496	(104,586)	64,495
Reportable Segment
Segment Reporting Information [Line Items]
Collaboration revenue	1,614			19,570			24,122	173,384
Total research and development expenses	38,361			31,257			108,312	91,900
General and administrative expenses	10,304			9,971			31,500	28,606
Interest and other income	3,571			5,766			11,936	14,346
Provision for (benefit from) income taxes	654			(1,860)			832	2,729
Net (loss) income	(44,134)			(14,032)			(104,586)	64,495
Reportable Segment | ENTR-601-44
Segment Reporting Information [Line Items]
Total research and development expenses	7,451			3,561			18,343	9,072
Reportable Segment | ENTR-601-45
Segment Reporting Information [Line Items]
Total research and development expenses	3,543			2,972			10,978	6,098
Reportable Segment | ENTR-601-50
Segment Reporting Information [Line Items]
Total research and development expenses	3,164			2,734			5,896	8,593
Reportable Segment | ENTR-601-51
Segment Reporting Information [Line Items]
Total research and development expenses	2,807			122			6,488	238
Reportable Segment | Collaboration services
Segment Reporting Information [Line Items]
Total research and development expenses	534			1,802			1,937	9,186
Reportable Segment | Other preclinical and discovery
Segment Reporting Information [Line Items]
Total research and development expenses	1,281			1,828			3,762	5,767
Reportable Segment | Personnel related (including stock-based compensation)
Segment Reporting Information [Line Items]
Total research and development expenses	11,549			10,875			37,536	30,687
Reportable Segment | Facility related and other
Segment Reporting Information [Line Items]
Total research and development expenses	$ 8,032			$ 7,363			$ 23,372	$ 22,259