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Segment Information - Operating Segment Information (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Segment Reporting Information [Line Items]    
Revenue $ 20,558 $ 59,120
Research and development 32,074 28,608
General and administrative 10,274 9,399
Interest and other income 4,441 4,214
Provision for income taxes 0 1,831
Net (loss) income (17,349) 23,496
Reportable Segment    
Segment Reporting Information [Line Items]    
Revenue 20,558 59,120
Research and development 32,074 28,608
General and administrative 10,274 9,399
Interest and other income 4,441 4,214
Provision for income taxes 0 1,831
Net (loss) income (17,349) 23,496
Reportable Segment | ENTR-601-44    
Segment Reporting Information [Line Items]    
Research and development 4,734 3,279
Reportable Segment | ENTR-601-45    
Segment Reporting Information [Line Items]    
Research and development 2,859 2,538
Reportable Segment | ENTR-601-50    
Segment Reporting Information [Line Items]    
Research and development 692 2,643
Reportable Segment | ENTR-601-51    
Segment Reporting Information [Line Items]    
Research and development 826 70
Reportable Segment | Collaboration services    
Segment Reporting Information [Line Items]    
Research and development 876 753
Reportable Segment | Other preclinical and discovery    
Segment Reporting Information [Line Items]    
Research and development 1,257 1,911
Reportable Segment | Personnel related (including stock-based compensation)    
Segment Reporting Information [Line Items]    
Research and development 12,756 9,900
Reportable Segment | Facility related and other    
Segment Reporting Information [Line Items]    
Research and development $ 8,074 $ 7,514