Collaboration and License Agreements - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Feb. 28, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	$ 20,558	$ 59,120
Vertex
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Strategic collaboration agreement, term			4 years
Revenue	20,600	58,100
Cumulative catch-up adjustment	12,300	17,400
Vertex | Recognition of upfront and milestone payments
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	18,900	38,700
Vertex | Collaboration service revenue
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	1,600	$ 2,000
Vertex | License
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue, remaining performance obligation, amount	$ 1,700