Segment Information - Operating Segment Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Segment Reporting Information [Line Items]
Collaboration revenue	$ 210,782	$ 129,013
Research and development	125,306	99,884
General and administrative	38,465	32,291
Interest and other income	19,474	15,218
Provision for income taxes	(859)	(18,741)
Net income (loss)	65,626	(6,685)
Reportable Segment
Segment Reporting Information [Line Items]
Collaboration revenue	210,782	129,013
Research and development	125,306	99,884
General and administrative	38,465	32,291
Interest and other income	19,474	15,218
Provision for income taxes	859	18,741
Net income (loss)	65,626	(6,685)
Reportable Segment | ENTR-601-44
Segment Reporting Information [Line Items]
Research and development	13,109	10,043
Reportable Segment | ENTR-601-45
Segment Reporting Information [Line Items]
Research and development	8,584	9,782
Reportable Segment | ENTR-601-50
Segment Reporting Information [Line Items]
Research and development	10,851	3,016
Reportable Segment | ENTR-601-51
Segment Reporting Information [Line Items]
Research and development	1,345	1,531
Reportable Segment | Collaboration services
Segment Reporting Information [Line Items]
Research and development	12,074	11,970
Reportable Segment | Other preclinical and discovery
Segment Reporting Information [Line Items]
Research and development	7,926	6,712
Reportable Segment | Personnel related (including stock-based compensation)
Segment Reporting Information [Line Items]
Research and development	41,762	31,250
Reportable Segment | Facility related and other
Segment Reporting Information [Line Items]
Research and development	$ 29,655	$ 25,580