CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY - USD ($) $ in Thousands	Total	Common Stock	Additional Paid‑in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022		31,394,767
Beginning balance at Dec. 31, 2022	$ 212,554	$ 3	$ 402,893	$ (2,057)	$ (188,285)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		214,078
Issuance of common stock upon exercise of stock options	1,187		1,187
Issuance of common stock in connection with the Vertex Agreement (in shares)		1,618,613
Issuance of common stock in connection with the Vertex Agreement	$ 19,407		19,407
Vesting of early exercised options (in shares)	14,745	33,416
Vesting of early exercised options	$ 91		91
Vesting of restricted stock units (in shares)		138,361
Purchase of common stock under the employee stock purchase plan (in shares)		38,061
Purchase of common stock under the employee stock purchase plan	443		443
Stock‑based compensation	13,111		13,111
Other comprehensive income (loss)	2,252			2,252
Net income (loss)	$ (6,685)				(6,685)
Ending balance (in shares) at Dec. 31, 2023	33,437,296	33,437,296
Ending balance at Dec. 31, 2023	$ 242,360	$ 3	437,132	195	(194,970)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)	377,669	377,669
Issuance of common stock upon exercise of stock options	$ 2,782		2,782
Issuance of common stock in connection with the Vertex Agreement (in shares)		3,367,003
Issuance of common stock in connection with the Vertex Agreement	$ 99,608	$ 1	99,607
Vesting of early exercised options (in shares)	1,676	13,069
Vesting of early exercised options	$ 51		51
Vesting of restricted stock units (in shares)		333,537
Purchase of common stock under the employee stock purchase plan (in shares)		45,964
Purchase of common stock under the employee stock purchase plan	574		574
Stock‑based compensation	17,915		17,915
Other comprehensive income (loss)	(238)			(238)
Net income (loss)	$ 65,626				65,626
Ending balance (in shares) at Dec. 31, 2024	37,574,538	37,574,538
Ending balance at Dec. 31, 2024	$ 428,678	$ 4	$ 558,061	$ (43)	$ (129,344)