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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Cash flows from operating activities:    
Net income $ 64,495 $ 2,859
Adjustments to reconcile net income to net cash (used in) provided by operating activities:    
Depreciation expense 2,781 2,105
Stock‑based compensation expense 13,215 9,270
Amortization/(accretion) of marketable securities (7,511) (3,780)
Changes in operating assets and liabilities:    
Collaboration receivable 3,275 (5,025)
Prepaid expenses and other current assets (1,464) (3,894)
Right-of-use assets, operating leases 7,717 11,146
Other non-current assets 2,044 (11,754)
Accounts payable (1,855) (5,211)
Accrued expenses and other current liabilities 2,133 1,857
Income tax payable (1,773) 0
Operating lease liabilities (6,916) (12,703)
Deferred revenue (86,093) 158,946
Net cash (used in) provided by operating activities (9,952) 143,816
Cash flows from investing activities:    
Purchases of property and equipment (2,523) (4,638)
Purchases of marketable securities (373,220) (318,686)
Maturities of marketable securities 294,580 165,886
Net cash (used in) investing activities (81,163) (157,438)
Cash flows from financing activities:    
Proceeds from exercise of stock options 1,691 754
Proceeds from issuance of common stock under the employee stock purchase plan 263 186
Net cash provided by financing activities 101,562 20,347
Net increase in cash, cash equivalents, and restricted cash 10,447 6,725
Cash, cash equivalents, and restricted cash at beginning of period 71,552 49,107
Cash, cash equivalents, and restricted cash at end of period 81,999 55,832
Supplemental cash flow disclosures:    
Purchases of property and equipment included in accounts payable and accrued expenses 60 299
Right-of-use assets obtained in exchange from operating lease liabilities 0 77,584
Right-of-use assets surrendered as part of lease modification 0 7,761
Transfer of deposits for equipment from operating to investing cash flows 0 617
Vesting of options early exercised subject to repurchase 38 72
Registered Direct Offering    
Cash flows from financing activities:    
Proceeds from issuance of common stock 99,608 0
Vertex Agreement    
Cash flows from financing activities:    
Proceeds from issuance of common stock $ 0 $ 19,407